1999
DOI: 10.1590/s0037-86821999000300002
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Abstract: Leishmaniasis is a typical parasite infection whose protective immunity depends on macrophage activation. Susceptibility to Leishmania donovani infection was compared in H (high antibody responder) and L (low antibody responder) mice from selection IV-

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Cited by 5 publications
(2 citation statements)
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“…Protective response was reflected in a lower footpad lesion, splenic index and parasite load; however, it must be improved. The reduction in splenic index could be indirectly related to a decrease in parasite visceralisation, (32) an inflammatory responses and to a lower susceptibility to infection. (33) Despite of the most conserved protein profile of sTLA, our previous studies with fTLA demonstrated an apparent higher protection, with lower footpad swelling.…”
Section: Discussionmentioning
confidence: 99%
“…Protective response was reflected in a lower footpad lesion, splenic index and parasite load; however, it must be improved. The reduction in splenic index could be indirectly related to a decrease in parasite visceralisation, (32) an inflammatory responses and to a lower susceptibility to infection. (33) Despite of the most conserved protein profile of sTLA, our previous studies with fTLA demonstrated an apparent higher protection, with lower footpad swelling.…”
Section: Discussionmentioning
confidence: 99%
“…This reduction in splenic index might indicate a decrease in parasite visceralization due the treatment. 23 …”
Section: Discussionmentioning
confidence: 99%