Leishmaniose causada por Leishmania viannia braziliensis (Lvb) um caso de evolução atípica

Costa, Jackson Maurício Lopes; Vale, Kyola Costa; França, Francisco Oscar de Siqueira; Lago, Ednaldo; Magalhães, Albino Verçosa de; Marsden, Philip D.; Sampaio, Raimunda Nonata Ribeiro

doi:10.1590/s0037-86821988000200008

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“…Reports of atypical forms of ATL have been described sporadically9–12. Herein, we described the frequency of atypical forms of ATL in a large cohort and compared clinical and immunologic characteristics of 19 patients with atypical ATL compared to those with classic ATL diagnosed in the study period.…”

Section: Discussionmentioning

confidence: 99%

Atypical manifestations of tegumentary leishmaniasis in a transmission area of Leishmania braziliensis in the state of Bahia, Brazil

Guimarães

Machado

Lago

et al. 2009

Transactions of the Royal Society of Tropical Medicine and Hygi

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Summary American tegumentary leishmaniasis (ATL) can occur in different forms, classically categorized as cutaneous leishmaniasis (CL), mucosal leishmaniasis (ML), diffuse cutaneous leishmaniasis and disseminated leishmaniasis. Atypical ATL have been described in sporadic case reports. In this study we analyzed the presence of atypical manifestations (vegetative, verrucous, crusted and lupoid) among a cohort of all patients presenting to the Health Post of Corte de Pedra. Among 1396 patients diagnosed with ATL in 2005–06, 35 (2.5%) patients presented with atypical manifestations of the disease. Of these patients, 14 were pregnant women, 2 were co-infected with HIV, and 19 had no comorbidity or other apparent risk factors for the development of atypical ATL. These 19 patients were the focus of this study. They were predominantly adult males, frequently presenting with facial lesions (p< 0.001 OR=17.5 CI 95% 6.1 – 52.4) and had higher rates of treatment failure with antimony therapy (p< 0.001 OR= 327 CI 95% 45 – 6668) when compared with patients with classic ATL attended in the same period.

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Section: Discussionmentioning

confidence: 99%