Antibody levels to hantavirus in inhabitants of western Santa Catarina State, Brazil

Souza, William Marciel de; Machado, Alex Martins; Disner, Geonildo Rodrigo; Boff, Everton; Machado, Aline Rafaela da Silva Rodrigues; Pádua, Michelly de; Figueiredo, Luíz Tadeu Moraes; Miranda, Gustavo Borba de

doi:10.1590/s0036-46652012000400002

Cited by 8 publications

(8 citation statements)

References 27 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The seroprevalence of anti-hantavirus IgG antibodies detected in this study is higher than that reported in the serological survey conducted by Souza et al 10 Despite using similar techniques, they observed 1.97% seroprevalence in the samples from the urban and rural areas of four municipalities of the Santa Catarina State. In another study conducted in cities near the border between Brazil and Argentina, still in the State of Santa Catarina, they found a 3.5% seroprevalence 11 .…”

contrasting

confidence: 87%

Seropositivity diagnosis for hantavirus in Jataí, Goiás State, Brazil

Moreli

Novaes

Flor³

et al. 2017

Rev. Soc. Bras. Med. Trop.

View full text Add to dashboard Cite

Introduction: Emerging diseases are of great interest, especially those associated with high mortality rates such as hantaviruses. We aimed to conduct a seroepidemiological survey to determine the levels of hantavirus infection. Methods: In-house enzyme-linked immunosorbent assay (ELISA) was used to detect specific antibodies. Results: Of the 429 samples collected, seropositivity of 3.9% to anti-hantavirus immunoglobulin G (IgG) was observed (CI 95%: 2.3-5.7). Moreover, in three cases, immunoglobulin M (IgM) was detected, of which two were diagnosed as hantavirus cardiopulmonary syndrome (HCPS). Conclusions: Our data indicate the considerable occurrence of previous hantavirus infections, highlighting occurrences from sub-clinical cases to HCPS.

show abstract

contrasting

confidence: 87%

Seropositivity diagnosis for hantavirus in Jataí, Goiás State, Brazil

Moreli

Novaes

Flor³

et al. 2017

Rev. Soc. Bras. Med. Trop.

View full text Add to dashboard Cite

show abstract

“…Considering that blood donors are commonly local inhabitants, it is possible that hantaviruses are circulating across practically all of the state. Of note, a study including 340 individuals inhabiting two cities in the western border of the state of Santa Catarina with Argentina, found 3.5% of individuals to be seropositive for hantavirus 7 . It might be worth noting that hantavirus infection is usually acquired by contact with wild rodents, often in the rural areas, and not in the urban environment.…”

Section: Resultsmentioning

confidence: 99%

Serologic Survey on Hantavirus in Blood Donors From the State of Santa Catarina, Brazil

Córdova

Figueiredo

2014

Rev. Inst. Med. trop. S. Paulo

Self Cite

View full text Add to dashboard Cite

Emergent diseases such as Hantavirus Cardio-pulmonary Syndrome (HCPS) are able to create a significant impact on human populations due to their seriousness and high fatality rate. Santa Catarina, located in the South of Brazil, is the leading state for HCPS with 267 reported cases from 1999 to 2011. We present here a serological survey on hantavirus in blood donors from different cities of the state of Santa Catarina, with an IgG-ELISA using a recombinant nucleocapsid protein from Araraquara hantavirus as an antigen. In total, 314 donors from blood banks participated in the study, geographically covering the whole state. Among these, 14 individuals (4.4%) had antibodies to hantavirus: four of 50 (8% positivity) from Blumenau, four of 52 (7.6%) from Joinville, three of 50 (6%) from Florianópolis, two of 50 (4%) from Chapecó and one of 35 (2.8%) from Joaçaba. It is possible that hantaviruses are circulating across almost the whole state, with important epidemiological implications. Considering that the seropositive blood donors are healthy individuals, it is possible that hantaviruses may be causing unrecognized infections, which are either asymptomatic or clinically nonspecific, in addition to HCPS. It is also possible that more than one hantavirus type could be circulating in this region, causing mostly benign infections.

show abstract

“…Cases of hantaviruses in Minas Gerais State have been described since 1998, and the Southeastern region of the state accumulates most of the cases 3,4 . Several serological studies conducted in the country have presented evidence of hantavirus circulation in different human populations in the absence of reported HPS 2,[4][5][6][7][8][9] . This suggests the possibility of silent virus transmission and consequently an underestimation of the virus's spatial distribution.…”

mentioning

confidence: 99%

“…Such activities are usually not related to planting and harvesting, camping, or hunting, which are known risk factors for acquiring Hantavirus infections [7][8][9] .…”

mentioning

confidence: 99%

Could hantavirus circulation superpose areas of highly endemic vaccinia virus outbreaks? A retrospective seroepidemiological study in State of Minas Gerais

Trindade

Fernandes

Costa

et al. 2014

Rev. Soc. Bras. Med. Trop.

Self Cite

View full text Add to dashboard Cite

Introduction: Hantavirus infections have been described in several regions in Brazil through seroepidemiological studies. Usually, populations are associated with rural and wild environment mainly due to close contact to species of Sigmodontinae rodents, considered hantavirus reservoirs. Methods: A retrospective serosurvey was conducted to access the hantavirus seroprevalence in people living in regions affected by bovine vaccinia outbreaks. Results: Sera from 53 patients were analyzed and none of them presented anti-hantavirus IgG antibodies. Conclusions: This study presents an opportunity to analyze seronegativity despite close and recurrent contact with known hantavirus reservoirs. Aspects of hantavirus and bovine vaccinia emergence are also discussed.

show abstract

Antibody levels to hantavirus in inhabitants of western Santa Catarina State, Brazil

Cited by 8 publications

References 27 publications

Seropositivity diagnosis for hantavirus in Jataí, Goiás State, Brazil

Seropositivity diagnosis for hantavirus in Jataí, Goiás State, Brazil

Serologic Survey on Hantavirus in Blood Donors From the State of Santa Catarina, Brazil

Could hantavirus circulation superpose areas of highly endemic vaccinia virus outbreaks? A retrospective seroepidemiological study in State of Minas Gerais

Contact Info

Product

Resources

About