2010
DOI: 10.1590/s0036-46652010000500007
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Abstract: Canine visceral leishmaniasis (CVL) is recognizable by characteristic signs of disease and is highly lethal. The infection, however, may be quite inapparent in some seropositive dogs, and this has raised the polemic question as to whether or not such animals can be a source of infection for Lutzomyia longipalpis, the vector of American visceral leishmaniasis (AVL). In this study we have examined 51 dogs with acute CVL from an AVL area in Pará State, northern Brazil, and compared the parasite density, amastigot… Show more

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Cited by 27 publications
(29 citation statements)
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“…Authors point out the skin as an important site for Leishmania detection due to its high parasite load in both asymptomatic and symptomatic animals (Lima et al 2010, Queiroz et al 2011. In the study conducted by Madeira et al (2009a), where 394 dogs seropositive for leishmaniasis were investigated, L. chagasi was isolated from the skin in 78% of the animals studied.…”
Section: Discussionmentioning
confidence: 99%
“…Authors point out the skin as an important site for Leishmania detection due to its high parasite load in both asymptomatic and symptomatic animals (Lima et al 2010, Queiroz et al 2011. In the study conducted by Madeira et al (2009a), where 394 dogs seropositive for leishmaniasis were investigated, L. chagasi was isolated from the skin in 78% of the animals studied.…”
Section: Discussionmentioning
confidence: 99%
“…Lima et al (2010) ainda relataram que animais sintomáticos para LVC tendem a apresentar altos títulos de anticorpos, geralmente superiores a 1:80, semelhante ao observado neste estudo, visto que a maioria dos animais não apresentava sinais clínicos característicos de LVC justificando, desse modo, a baixa ocorrência de reações com diluição acima de 1:80 dentre as amostras soropositivas (33,33% até a diluição de 1:160 e 3,33% até a diluição 1:320).…”
Section: Discussionunclassified
“…Os achados do presente estudo ratificam que Belém ainda pode ser considerada área não endêmica para LVC, contudo, vale ressaltar que há vários municípios da região metropolitana de Belém (Lima et al 2010, Brasil 2012 bem como municípios próximos situados na Ilha do Marajó (Quinnel et al 2001, Brasil 2012 e na região nordeste do Estado do Pará (Brasil 2012) que são considerados de alta taxa de transmissão e apresentam elevada taxa de êxodo para a capital, demonstrando a necessidade de um sistema de vigilância constante e eficaz para o monitoramento de casos de LVC.…”
Section: Conclusõesunclassified
“…Canines, particularly symptomatic and asymptomatic domestic dogs, act as a source of parasites for VL transmission 85 and canine visceral leishmaniasis (CVL) is a significant public health issue. The development of a CVL vaccine represents a cost-effective tool for interrupting the transmission cycle and may be crucial for controlling VL infection in humans.…”
Section: Canine Visceral Leishmaniasis Vaccinementioning
confidence: 99%