2010
DOI: 10.1590/s0036-46652010000200010
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Abstract: Dear Sir:Chagas disease (CD) is very prevalent in South America, with wellknown manifestations in the digestive system. CD esophagopathy leads to a clinical and manometric picture similar to idiopathic (primary) achalasia 4 . Although the treatment for CD esophagopathy is well established 3 , South American surgeons and gastroenterologists are sometimes faced with CD patients without esophageal involvement but with gastroesophageal reflux disease (GERD) complaints. Surgical therapy in these patients may be deb… Show more

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Cited by 2 publications
(3 citation statements)
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“…However, this motor alteration was not observed when a cohort of non‐symptomatic healthy subjects of the same origin were studied, and the prevalence and frequency of typical reflux symptoms (heartburn and regurgitation) were similar whether or not ineffective motility was present at HREM. Previous studies evaluating the association between Chagas disease and gastrooesophageal reflux could not demonstrate a clear association between them, even though Troncon et al found that patients with Chagas disease have a tendency to develop reflux 23 , 24 . Hence, even though neither heartburn nor regurgitation was associated with ineffective oesophageal motility, we cannot exclude the possibility that an association between reflux and T. cruzi infection exists.…”
Section: Discussionmentioning
confidence: 62%
See 1 more Smart Citation
“…However, this motor alteration was not observed when a cohort of non‐symptomatic healthy subjects of the same origin were studied, and the prevalence and frequency of typical reflux symptoms (heartburn and regurgitation) were similar whether or not ineffective motility was present at HREM. Previous studies evaluating the association between Chagas disease and gastrooesophageal reflux could not demonstrate a clear association between them, even though Troncon et al found that patients with Chagas disease have a tendency to develop reflux 23 , 24 . Hence, even though neither heartburn nor regurgitation was associated with ineffective oesophageal motility, we cannot exclude the possibility that an association between reflux and T. cruzi infection exists.…”
Section: Discussionmentioning
confidence: 62%
“…Previous studies evaluating the association between Chagas disease and gastrooesophageal reflux could not demonstrate a clear association between them, even though Troncon et al found that patients with Chagas disease have a tendency to develop reflux. 23,24 Hence, even though neither heartburn nor regurgitation was associated with ineffective oesophageal motility, we cannot exclude the possibility that an association between reflux and T. cruzi infection exists. To note, dysphagia and chest pain were more frequently referred by patients with normal manometry.…”
Section: Discussionmentioning
confidence: 94%
“…On the one hand, researchers who have the chance to study patients with positive serological tests for CDE before esophageal symptoms may manifest what does not occur in idiopathic achalasia. On the other hand, patients with Chagas disease may never develop CDE but may present with other esophageal diseases such as gastroesophageal reflux disease (GERD) 7 . Chicago Classification 4.0 clarified that primary esophageal motility disorders should only be considered in the absence of GERD and, as such, all these cases of an “undetermined” phase must undergo pH monitoring.…”
mentioning
confidence: 99%