Duality of patterns in hepatitis a epidemiology: A study involving two socioeconomically distinct populations  in Campinas, São Paulo state, Brazil

Pinho, João Renato Rebello; Sumita, Laura Masami; Moreira, R.; Souza, Vanda Akico Ueda Fick de; Saraceni, Cláudia Patara; Oba, Isabel Takano; Carvalho, M. C. S.; Pannuti, Cláudio Sérgio

doi:10.1590/s0036-46651998000200007

Cited by 33 publications

(22 citation statements)

References 5 publications

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“…The city has 346,878 inhabitants 17 , living in the urban periphery (low our low-middle socioeconomic status) and in the downtown, near the beach (high socioeconomic status). 32 Rio de Janeiro, RJ NA 97 Oliveira et al 21 Rio de Janeiro, RJ NA 54.3 Queiroz et al 25 Goiânia, GO 80 92.9 Queiroz et al 26 Goiânia, GO 69.7 NA Ferreira et a l8 Porto Alegre, RS 7*/53** 17*/71** Pinho et al 24 Campinas, SP NA 19.6*/95** Vitral et al 31 Rio de Janeiro, RJ 34% 66 Focaccia et al 10 São Paulo, SP 28% 56 Struchiner et al 28 Rio de Janeiro, RJ 12*/36.6** NA Clemens et al 6 Manaus 2 3 Duque de Caxias, RJ 60.3 89.4 * high socioeconomic class; ** low socioeconomic; # urban population; ## rural population; NA not available.…”

Section: Methodsmentioning

confidence: 99%

Prevalence of anti-hepatits A antibodies in children of different socioeconomic conditions in Vila Velha, ES

Zago-Gomes

Stantolin

Perazzio

et al. 2005

Rev. Soc. Bras. Med. Trop.

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Section: Methodsmentioning

confidence: 99%

Prevalence of anti-hepatits A antibodies in children of different socioeconomic conditions in Vila Velha, ES

Zago-Gomes

Stantolin

Perazzio

et al. 2005

Rev. Soc. Bras. Med. Trop.

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“…Most acute and/or chronic hepatitis cases result from infection with one of the hepatitis viruses, named from A to E. In Brazil different patterns of hepatitis viruses distribution are found throughout the country. Hepatitis A virus (HAV) infection is endemic especially among low socioeconomic populations, although a decrease in its prevalence has been observed recently in areas where sanitary conditions have been improving (Pinho et al 1998, Vitral et al 1998a. Hepatitis E virus (HEV) is considered a major etiological agent of enterically-transmitted viral hepatitis in several developing countries.…”

Section: Very High Prevalence Of Delta Hepatitis (666%) Was Found Ammentioning

confidence: 99%

Seroprevalence of viral hepatitis in riverine communities from the Western Region of the Brazilian Amazon Basin

Paula

Arruda

Vitral

et al. 2001

Mem. Inst. Oswaldo Cruz

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“…The prevalence of anti-HEV antibodies in blood donors from Campinas was lower than that of anti-HAV antibodies (20). This fact can be explained four different ways.…”

Section: Discussionmentioning

confidence: 90%

Hepatitis E Virus Immunoglobulin G Antibodies in Different Populations in Campinas, Brazil

Gonçales

Pinho

Moreira

et al. 2000

Clin Diagn Lab Immunol

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The seroprevalence of anti-hepatitis E virus (HEV) antibodies was investigated by enzyme immunoassay in 205 volunteer blood donors, 214 women who attended a center for anonymous testing for human immunodeficiency virus (HIV) infection, and 170 hospital employees in Campinas, a city in southeastern Brazil. The prevalence of anti-HEV antibodies ranged from 2.6% (3 of 117) in health care professionals to 17.7% (38 of 214) in women who considered themselves at risk for HIV. The prevalence of anti-HEV antibodies in health care professionals was not significantly different from that in healthy blood donors (3.0%, 5 of 165) and blood donors with raised alanine aminotransferase levels (7.5%, 3 of 40). The prevalence of anti-HEV antibodies (13.2%, 7 of 53) in cleaning service workers at a University hospital was similar to that among women at risk for HIV infection. These results suggest that HEV is circulating in southeastern Brazil and that low socioeconomic status is an important risk factor for HEV infection in this region.Hepatitis E virus (HEV) is considered the main etiologic agent of enterically transmitted non-A, non-B hepatitis (ET-NANBH) and occurs in epidemics or sporadically. ET-NANBH, once thought to be a disease confined to developing countries, is now recognized to have a wider geographical distribution (12,33). Epidemics have been related to contaminated water supplies, as fecal-oral transmission is the major route of transmission (29). The symptoms of ET-NANBH are similar to those of hepatitis A, although it affects primarily young adult populations already immune to hepatitis A virus (HAV). HEV is well recognized as a cause of fulminant hepatic failure in areas where it is endemic (23), particularly in pregnant women who contract it in the third trimester (10). In developed countries, sporadic cases have been identified among travelers from areas where it is endemic and HEV has been implicated in some community-acquired cases of NANBH in the United States and other western countries (12).Until recently, the diagnosis of ET-NANBH was based on serology after the exclusion of other viral hepatitis. In 1990, the isolation of a partial cDNA clone from HEV (22) led to the identification of type-common immunodominant epitopes and the development of diagnostic serological assays for the detection of antibodies to recombinant HEV antigens (4).The prevalence of HEV infection among blood donors in developed countries ranges from 0.4 to 3.9% (4,14,15). An association between HEV and hepatitis C virus infections has been reported, suggesting similar or overlapping routes of transmission (21). In addition, a higher prevalence of antibodies to HEV has been reported among patients undergoing chronic hemodialysis (9), suggesting that this virus is also spread by the parenteral route. Homosexual men also have a high prevalence of HEV infection (15), and the possibility of sexual transmission cannot be neglected. Few studies have addressed the prevalence of HEV infection in Brazil because diagnostic tests for this illnes...

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Duality of patterns in hepatitis a epidemiology: A study involving two socioeconomically distinct populations in Campinas, São Paulo state, Brazil

Cited by 33 publications

References 5 publications

Prevalence of anti-hepatits A antibodies in children of different socioeconomic conditions in Vila Velha, ES

Prevalence of anti-hepatits A antibodies in children of different socioeconomic conditions in Vila Velha, ES

Seroprevalence of viral hepatitis in riverine communities from the Western Region of the Brazilian Amazon Basin

Hepatitis E Virus Immunoglobulin G Antibodies in Different Populations in Campinas, Brazil

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