Relative Frequency of Nosocomial Microorganisms at Unicamp University Hospital from 1987 to 1994

Abstract

The frequency of microorganisms identified in nosocomial infections at Unicamp University Hospital from 1987 to 1994 was analysed. The most common microorganism was S. aureus (20.9%), which was found in surgical wound, bloodstream and arterial-venous infections. In urinary tract infections (UTI), gram-negative rods (56.5%) and yeasts (9%) predominated. A. baumannii isolates were observed to have increased in the last three years. There was a gradual increase in the frequency of coagulase-negative staphylococci and A. baumannii in bloodstream infections but there wasn't any change in Candida sp.

The History of Methicillin-Resistant Staphylococcus aureus in Brazil

“…From 1987 to 1994, Tresoldi and colleagues reported that 257 of 421 S. aureus isolates were MRSA. However, although S. aureus is to be isolated with the highest frequency (20.9%), MRSA isolates in this study were reported only in the 1990s by Tresoldi and colleagues [ 18 ].…”

“…The theory of interhospital connection was reinforced when the same clone of MRSA was isolated from different locations at the same hospital in Joao Pessoa, in 1992 [ 36 ] and thereafter was found in the Campinas University Hospital, in two different studies [ 18 , 37 ]. Such a clone was shown to be the same one found by Sader et al in São Paulo, in 1993 and 1994 [ 31 , 32 ].…”

Bacteremias em pacientes internados em hospital universitário

“…Em estudo de hospital universitário paulista, também predominaram as bactérias gram-negativas 34 . Já em registros de hospital de ensino de Porto Alegre, RS, os patógenos gram-positivos foram mais freqüentes nas hemoculturas 32 .…”

“…nos últimos anos 9,18 . Quanto ao predomínio do S. aureus em bacteremias nosocomiais, resultados semelhantes aos nossos foram descritos em hospitais da região sul e sudeste brasileira 5,32,34 . Dados recentes do Programa de Vigilância Antimicrobiana Sentry confirmam a importância do S. aureus em ICS.…”

“…A elevada proporção de MRSA em nosso estudo é motivo de preocupação. Índices semelhantes aos nossos têm sido descritos 6,34,38 . Em relação à bacteremia por Staphylococcus coagulase negativa (SCN), a distinção entre bacteremia verdadeira ou contaminação nem sempre é facilmente estabelecida.…”