Transmissão da doença de Chagas por transplante renal: ocorrência da forma aguda da doença em dois receptores de um mesmo doador

Ferraz, Alexsander; Figueiredo, J F C

doi:10.1590/s0036-46651993000500013

Cited by 42 publications

References 1 publication

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Transmission ofT. cruzi infection via liver transplantation to a nonreactive recipient for Chagas' disease

Barcán

Lunaó²,

Clara

et al. 2005

Liver Transpl

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Chagas' disease is an endemic zoonosis of South America caused by a protozoan parasite Trypanosoma cruzi. About 30% of infected people develop the disease. This disease is known to reactivate in immunocompromised hosts, such as patients with acquired immunodeficiency syndrome, leukemia, and transplantation. There is some experience with transplantation of infected renal grafts into negative recipients, resulting in an index of transmission of 35%. No cases have been reported involving other organ transplants up to 2002, when the Centers for Disease Control and Prevention reported 3 cases of Chagas' disease transmission to 3 recipients (liver, kidney, and pancreas‐kidney) from a single chagas infected donor. Here we report on a case of orthotopic liver transplant from a chagas infected donor into a negative recipient in clinical emergency status. The recipient was monitored by direct parasitological Strout method and serological tests with detection of transmission on the 84th day by both studies, without clinical signs. The patient was put on benznidazole with rapid clearance of the parasitemia. However, we propose that chagas infected donors may be accepted for liver transplant recipients only in emergency status. (Liver Transpl 2005;11:1112–1116.)

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Transmission ofT. cruzi infection via liver transplantation to a nonreactive recipient for Chagas' disease

Barcán

Lunaó²,

Clara

et al. 2005

Liver Transpl

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Infectious Disease Aspects of the Brain-Dead Potential Organ Donor

Theodoropoulos

Ison²

2012

The Brain-Dead Organ Donor

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Chagas Disease: Coming to a Transplanted Patient Near You

Pierrotti

Ibrahim

2020

Emerging Transplant Infections

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Chagas disease is a vector-borne infection caused by the protozoan Trypanosoma cruzi that is endemic in Latin America. More recently, the geographic distribution of the disease has changed due to immigration of asymptomatic infected individuals from endemic to non-endemic regions. Therefore, Chagas disease involving acute infection among negative recipients receiving a transplant graft from positive donors and reactivation episodes among positive recipients due to posttransplant immunosuppression is a problem that has been recognized worldwide. This chapter aims to highlight the epidemiology, clinical manifestations, diagnosis, management, and outcomes of Chagas disease among transplant recipients.

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Transmissão da doença de Chagas por transplante renal: ocorrência da forma aguda da doença em dois receptores de um mesmo doador

Cited by 42 publications

References 1 publication

Transmission ofT. cruzi infection via liver transplantation to a nonreactive recipient for Chagas' disease

Transmission ofT. cruzi infection via liver transplantation to a nonreactive recipient for Chagas' disease

Infectious Disease Aspects of the Brain-Dead Potential Organ Donor

Chagas Disease: Coming to a Transplanted Patient Near You

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