Potential infectivity of blood from HBsAG asymptomatic carriers due to the presence of HBV-DNA and comparison with other markers of hbv infection

Tedeschi, M. V.; Padilla, Cláudia Figueiredo; Camargo, I. F.; Yoshida, Clara Fumiko Tachibana

doi:10.1590/s0036-46651989000600003

Cited by 2 publications

(1 citation statement)

References 21 publications

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“…These results are in agreement with the studies accomplished by TEDESCHI et al (1989) 38 and CHIARAMONTE et al (1991) 11 although they differ from other studies in which it has been observed higher indexes of detection for HBV-DNA by PCR 2,16,27 and Dot-blot 26 .…”

Section: Discussionsupporting

confidence: 90%

Seroprevalence of hepatitis B virus infection in individuals with clinical evidence of hepatitis in Goiânia, Goiás: detection of viral DNA and determination of subtypes

Silva

Azevedo

Soares

et al. 2002

Rev. Inst. Med. trop. S. Paulo

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SUMMARYThe presence of serological markers for hepatitis B virus (HBsAg, anti-HBc IgM and Anti-HBc total) was investigated in the serum of 1,396 individuals who had clinical suspect of hepatitis. It was observed that 50.7% of the individuals were positive and, from the total of the studied individuals, 14.5% were positive for HBsAg. From these, 8.5% were also positive for anti-HBc IgM. The analysis in relation to gender showed a higher seroprevalence index among male individuals (p < 0.0001). It was observed the occurrence of subtypes adw 2 (62.7%), ayw 3 (23.5%), ayw 2 (9.8%) and adw 4 (3.9%). The viral DNA was detected in 61 (33.9%) HBsAg positive samples and in one sample positive only for anti-HBc total. These results indicate an important incidence of the HBV infection in this population, and reinforce previous studies regarding this virus in the central west region of Brazil.

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Section: Discussionsupporting

confidence: 90%

Seroprevalence of hepatitis B virus infection in individuals with clinical evidence of hepatitis in Goiânia, Goiás: detection of viral DNA and determination of subtypes

Silva

Azevedo

Soares

et al. 2002

Rev. Inst. Med. trop. S. Paulo

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Assessment of hepatitis B"e" antigen and"e" antibody status--tests of status or status of tests?

Westmoreland

Parr²,

Thomas³

1994

Journal of Medical Microbiology

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Summary. Forty-seven sera that gave positive results in tests for hepatitis B surface antigen and core antibody were examined for the presence of " e " antigen and " e " antibody by various commercially available assays. Considerable discordance was observed between results of tests performed on the same sample in different assays. Examination of the sera for the presence of hepatitis B DNA failed to resolve the discrepancies. Increasingly, "e" antigen and its antibody are used as measures of infectivity in carriers of hepatitis B. The absence of reliable tests has implications for patients, for infection control within hospitals and for the implementation of Department of Health guidelines on safe working practices for hepatitis B-infected health care workers.

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Potential infectivity of blood from HBsAG asymptomatic carriers due to the presence of HBV-DNA and comparison with other markers of hbv infection

Abstract: SUMMARY

Cited by 2 publications

References 21 publications

Seroprevalence of hepatitis B virus infection in individuals with clinical evidence of hepatitis in Goiânia, Goiás: detection of viral DNA and determination of subtypes

Seroprevalence of hepatitis B virus infection in individuals with clinical evidence of hepatitis in Goiânia, Goiás: detection of viral DNA and determination of subtypes

Assessment of hepatitis B"e" antigen and"e" antibody status--tests of status or status of tests?

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