1989
DOI: 10.1590/s0036-46651989000100011
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Abstract: Of th e 2 1 patient s studied , 1 8 (85.72% ) sho wed improvemen t wit h clinica l remissio n an d(1) Professo r Assistente Doutor d

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Cited by 21 publications
(11 citation statements)
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“…In addition, this treatment regimen is highly available in the public network of health services. 13,20 The effectiveness of SMX-TMP varies among the few studies available. Barbosa and Vasconcelos (1973) 21 tested this treatment of the first time in Brazil and observed a 100% therapeutic success rate with lesion disappearance within a maximum of 35 days.…”
Section: Discussionmentioning
confidence: 99%
“…In addition, this treatment regimen is highly available in the public network of health services. 13,20 The effectiveness of SMX-TMP varies among the few studies available. Barbosa and Vasconcelos (1973) 21 tested this treatment of the first time in Brazil and observed a 100% therapeutic success rate with lesion disappearance within a maximum of 35 days.…”
Section: Discussionmentioning
confidence: 99%
“…Table 1 summarises the studies conducted by Brazilian investigators, whereas Table 2 displays those done by investigators from other South American countries. It can be seen from the tables [32][33][34][35][36][37][38][39][40][41][42][43][44][45][46][47][48][49][50][51], as well as from some other studies that specifically focused on the performance of serological techniques [11,12,22,25,[52][53][54][55][56], that antibody titres dropped with therapy but less frequently became negative when therapy was stopped or patients were considered clinically and mycologically cured, or both. In many reports, the fall in the antibody titres persisted even after withdrawal of the anti-fungal therapy.…”
Section: Discussionmentioning
confidence: 99%
“…The use of the trimethoprim-sulfonamide combination has been recommended as an alternative for patients with sulfadiazine-resistant isolates (173). Recently, attempts have been made to improve the efficacy of sulfadiazine by combining it with trimethoprim (cotrimazine) (17); preliminary results indicate that such a combination may be useful for the treatment of cerebral paracoccidioidomycosis, as both drugs penetrate the cerebrospinal blood barrier well (17).…”
Section: Opportunismmentioning
confidence: 99%