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Cited by 7 publications
(5 citation statements)
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“…The response of the specific immunoglobulin M antibody is not restricted to primary infections, as reactivation and reinfection may also cause an increase in immunoglobulin M titers. 13 Other disadvantages include false negative results and false positive results due to low titers resulting from cross-reaction to rheumatoid factor. 25 In this study, the polymerase chain reaction was used as the gold standard for infection diagnosis.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…The response of the specific immunoglobulin M antibody is not restricted to primary infections, as reactivation and reinfection may also cause an increase in immunoglobulin M titers. 13 Other disadvantages include false negative results and false positive results due to low titers resulting from cross-reaction to rheumatoid factor. 25 In this study, the polymerase chain reaction was used as the gold standard for infection diagnosis.…”
Section: Discussionmentioning
confidence: 99%
“…The presence of a specific immunoglobulin M antibody suggests active infection. [11][12][13] In 1985, Stagno and Whitley 10 performed a diagnostic study of cytomegalovirus in maternal blood using the ELISA and radio-immunoassay techniques to detect immunoglobulin M antibodies and reported approximately 95% specificity and 70% sensitivity.…”
Section: Introductionmentioning
confidence: 99%
“…With age the increased prevalence of antibodies is common. This may not depend on the geographical area, but the socio-economic status may be important [10,[23][24][25][26][27][28]. The seroprevalence of CMV in populations at high socioeconomic level varies from 40% to 60%, increases after infection of early childhood and approximately 10% to 20% of children have their first infection episode before puberty [10].…”
Section: Transmission and Epidemiologymentioning
confidence: 99%
“…1,2,6,8,10,13,19,23 Essa importância torna-se ainda mais evidente nesse contexto quando se observa que pode estar relacionada a uma miríade de complicações, como doenças oportunistas, rejeição celular aguda e crônica, infecções bacterianas, dentre outras. 18,[20][21][22][23][24][25][26][27][28][29][30][31][32] Nesse estudo, investigouse a incidência das infecções pelos betaherpesvírus HCMV, HHV-6 e HHV-7 através de N-PCR, antigenemia e sorologia, e procurou-se determinar as correlações dos testes aplicados com os possíveis fatores de riscos relacionados ao impacto clínico após o transplante de fígado. Observou-se uma prevalência de 87,5% de indivíduos soropositivos para HCMV (IgG positiva), no pré-transplante, sendo esse achado compatível com a da literatura, que aponta a prevalência de infecção por HCMV em torno de 80%-100% da população brasileira.21 Em relação ao HHV-6 não foi possível a realização da sorologia dos respectivos doadores para determinação de infecção primária, reinfecção ou reativação.…”
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