Relationship between the iron status of pregnant women and their newborns

Abstract

OBJECTIVE: To determine the relationship between iron nutritional status of pregnant women and their newborns using a combination of hematological and biochemical parameters for the diagnosis of iron defi ciency. METHODS:A cross-sectional study was conducted in Jundiaí, Southeastern Brazil, in 2000. Venous blood samples collected from 95 pregnant women and from their umbilical cord and used for the determination of complete blood count, serum iron, total iron-binding capacity, serum ferritin, zinc protoporphyrin, and transferrin saturation. Women were classifi ed into three groups: anemic, iron defi cient and non-iron defi cient. Statistical analysis included the Tukey-HSD test, Pearson's correlation coeffi cient and multiple linear regression analysis. RESULTS:Among pregnant women, 19% were anemic (97.9% mildly anemic and 2.1% moderately anemic) and 30.5% were iron defi cient. No signifi cant difference was seen in mean values of any parameter studied between newborns in the three groups (p>0.05). Multiple linear regression analysis showed weak association between neonatal and maternal parameters. CONCLUSIONS:The iron nutritional status of pregnant women with iron defi ciency or mild anemia does not seem to have a signifi cant impact on the iron levels of their children.

Effect of Maternal Iron Deficiency Anemia on the Iron Store of Newborns in Ethiopia

“…These findings were in accordance with previous reports elsewhere [ 3 , 8 , 17 , 18 ]. However, there are also findings in contrary to the present study which showed that iron accretion in the fetus was independent of maternal iron status [ 12 – 14 ].…”

“…In spite of many researches conducted on this specific issue, consistent findings were not evident. Some have reported the negative impact of maternal IDA on iron stores of newborns [ 3 , 5 , 8 – 11 ], while others could not find any relationship in between [ 12 – 14 ]. Most of the studies have used serum ferritin as a measurement of iron store, but this serum ferritin has one known drawback as it is an acute phase reactant (APR); it increases during infection, including sub-clinical infections [ 15 ].…”

Prevalence of Undernutrition and Anemia among Santal Adivasi Children, Birbhum District, West Bengal, India

“…The association between maternal and child's anemia may have multiple causes, influenced by jointly experienced environmental risk factors. Still, while some studies found no association [79][80][81]; others suggest infants born to anemic or iron-deficient mothers being more likely to develop iron-deficiency anemia in the first year of life [82], or hemoglobin levels of exclusively breastfed infants being associated to maternal hemoglobin levels [83]. Equally, children of Nepal and Pakistan having an anemic mother were more prone to anemia [71].…”

The effect of third trimester maternal hemoglobin levels to fetal weight and the week of birth

“…(16) 2005'te 153.396 gebede yaptıkları çalışmada, 13.204 (%8,6) anemik gebe saptamışlar ve maternal aneminin düşük doğum ağırlığı ve erken doğuma neden olduğunu göstermişlerdir.…”

“…(16) 2007'de 95 gebede yaptıkları çalışmada anemik ve anemik olmayan gebeler arasında yenidoğan doğum kilosu açısından fark saptamamışlardır. Gebelerin %19'unda anemi saptamış-lardır.…”