Brucella canis: inquéritos sorológico e bacteriológico em população felina

Larsson, Maria; Larsson, Carlos Eduardo; Fernandes, Wilson Roberto; Costa, Elizabeth Oliveira da; Hagiwara, Mitika K.

doi:10.1590/s0034-89101984000100005

Cited by 4 publications

(4 citation statements)

References 5 publications

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“…In addition to being found in dogs, anti-B. canis antibodies have also been detected in wild canids (130,131), and domestic and wild felines (131)(132)(133), although felines are considered resistant to brucellosis (130). There is serological evidence of antibodies anti-B.…”

Section: Epidemiology Of Canine Brucellosismentioning

confidence: 99%

Canine Brucellosis: An Update

et al. 2021

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Canine brucellosis is an infectious and zoonotic disease caused by Brucella canis, which has been reported worldwide, and is a major public health concern due to close contact between dogs and humans. In dogs, canine brucellosis manifests with abortion outbreaks, reproductive failure, enlargement of lymph nodes, and occasionally affects the osteoarticular system, although the occurrence of asymptomatic infections in dogs are not uncommon. In humans, the disease is associated with a febrile syndrome, commonly with non-specific symptoms including splenomegaly, fatigue, and weakness. Infection of dogs occurs mostly by the oronasal route when in contact with contaminated tissues such as aborted fetuses, semen, urine, and vaginal secretions. In humans, contact with contaminated fluids from infected dogs is an important source of infection, and it is an occupational risk for veterinarians, breeders, laboratory workers, among other professionals who deal with infected animals or biological samples. The diagnosis in dogs is largely based on serologic methods. However, serologic diagnosis of canine brucellosis remains very challenging due to the low accuracy of available tests. Molecular diagnostic methods have been increasingly used in the past few years. Treatment of infected dogs is associated with a high frequency of relapse, and should be employed only in selected cases. Currently there are no commercially available vaccines for prevention of canine brucellosis. Therefore, development of novel and improved diagnostic methods as well as the development of efficacious and safe vaccination protocols are needed for an effective control of canine brucellosis and its associated zoonotic risk.

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Section: Epidemiology Of Canine Brucellosismentioning

confidence: 99%

Canine Brucellosis: An Update

et al. 2021

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“…20,21 Molecular oxygen is also a viable oxidant, typically when used in combination with one or more redox active cocatalysts to facilitate regeneration of the Pd II catalyst. [22][23][24][25][26][27][28][29][30] The development of ligand-supported catalyst systems has stimulated renewed interest in Pd-catalyzed allylic oxidation reactions in recent years. 7,8,12,31 These catalyst systems, which contrast the simple Pd II salts [e.g., PdCl 2 or Pd(OAc) 2 ] primarily employed as catalysts during the first four decades of the field, facilitate catalyst optimization efforts and introduce new opportunities to achieve catalyst controlled selectivity in the reactions.…”

Section: Introductionmentioning

confidence: 99%

Operando Spectroscopic and Kinetic Characterization of Aerobic Allylic C–H Acetoxylation Catalyzed by Pd(OAc)₂/4,5-Diazafluoren-9-one

et al. 2019

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Allylic C-H acetoxylations are among the most widely studied palladium(II)-catalyzed C-H oxidation reactions. While the principal reaction steps are well established, key features of the catalytic mechanisms are poorly characterized, including the identity of the turnover-limiting step and the catalyst resting state. Here, we report a mechanistic study of aerobic allylic acetoxylation of allylbenzene with a catalyst system composed of Pd(OAc) 2 and 4,5-diazafluoren-9-one (DAF). The DAF ligand is unique in its ability to support aerobic catalytic turnover, even in the absence of benzoquinone or other co-catalysts. Herein, we describe operando spectroscopic analysis of the catalytic reaction using X-ray absorption and NMR spectroscopic methods that allow direct observation of the formation and decay of a palladium(I) species during the reaction. Kinetic studies reveal the presence of two distinct kinetic phases: (1) a burst phase, involving rapid formation of the allylic acetoxylation product and formation of the dimeric Pd I complex [Pd I (DAF)(OAc)] 2 , followed by (2) a post-burst phase that coincides with evolution of the catalyst resting state from the Pd I dimer into a π-allyl-Pd II species. The data provide unprecedented insights into the role of ancillary ligands in supporting catalytic turnover with O 2 as the stoichiometric oxidant and establish an important foundation for the development of improved catalysts for allylic oxidation reactions.

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“…In the present study, B. abortus and B. canis infections were detected by serological and molecular methods in three different species of wild felids kept in captivity in Brazil. Few studies have demonstrated the infection by the Brucella agent in cats, either wild (Nava, ) or domestic (Larsson et al ., ). Usually, B. abortus infection is associated with the habit of feeding on placental membranes or aborted fetuses from infected cattle.…”

Section: Resultsmentioning

confidence: 97%

“…Other Brucella spp, such as B. canis , often affect domestic canidae and generally are transmitted venereally (Olsen, ). Brucella canis is rarely reported in wild animals and there is no report to date of its occurrence in wild felids, although it has been observed in domestic cats with a prevalence of 3–11⋅4% (Larsson et al ., ).…”

Section: Introductionmentioning

confidence: 97%

Brucella abortus and Brucella canis in captive wild felids in Brazil

Almeida

Silva

Pitchenin

et al. 2012

International Zoo Yearbook

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Blood samples were taken from seven Puma Puma concolor, five Jaguar Panthera onca, four Ocelot Leopardus pardalis and one Lion Panthera leo. Brucellosis serology and polymerase chain reaction were performed. The presence of antibodies and DNA of Brucella abortus and Brucella canis were not detected in P. leo. The amplification of DNA from B. abortus and B. canis was observed in the four Ocelot. DNA from B. abortus was detected in one Jaguar, and DNA from B. canis in two Puma and one Jaguar. Serology for B. abortus was positive in two Puma and two Jaguar, while B. canis was observed in one Ocelot and two Jaguar. Although not considered a source of infection to staff, multidisciplinary studies should be carried out to elucidate the role of domestic animals in the epidemiology of this zoonosis.

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Brucella canis: inquéritos sorológico e bacteriológico em população felina

Cited by 4 publications

References 5 publications

Canine Brucellosis: An Update

Canine Brucellosis: An Update

Operando Spectroscopic and Kinetic Characterization of Aerobic Allylic C–H Acetoxylation Catalyzed by Pd(OAc)₂/4,5-Diazafluoren-9-one

Brucella abortus and Brucella canis in captive wild felids in Brazil

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Brucella canis: inquéritos sorológico e bacteriológico em população felina

Cited by 4 publications

References 5 publications

Canine Brucellosis: An Update

Canine Brucellosis: An Update

Operando Spectroscopic and Kinetic Characterization of Aerobic Allylic C–H Acetoxylation Catalyzed by Pd(OAc)2/4,5-Diazafluoren-9-one

Brucella abortus and Brucella canis in captive wild felids in Brazil

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Operando Spectroscopic and Kinetic Characterization of Aerobic Allylic C–H Acetoxylation Catalyzed by Pd(OAc)₂/4,5-Diazafluoren-9-one