Metemoglobinemia: do diagnóstico ao tratamento

Abstract

Rev Bras AnestesiolARTIGO DIVERSO 2008; 58: 6: 651-664 MISCELLANEOUS RESUMO Nascimento TS, Pereira ROL, Mello HLD, Costa J -Metemoglobinemia: do Diagnóstico ao Tratamento. JUSTIFICATIVAS E OBJETIVOS: CONCLUSÃO:A metemoglobinemia é condição potencialmente grave, cujo diagnóstico depende do alto grau de suspeição. Em geral, os anestesiologistas, no período perioperatório, são os primeiros a detectarem o problema e devem liderar a condução do tratamento.

Blood Levels of Methemoglobin in Patients with Aluminum Phosphide Poisoning and its Correlation with Patient’s Outcome

“…Methemoglobinemia should be suspected in the presence of central cyanosis and low oxygen saturation (SpO 2 ) on pulse oximetry in the absence of more prevalent causes of hypoxia such as cardiopulmonary dysfunctions [14]. Clinical manifestations of methemoglobinemia depend on blood concentration of Met-Hb and vary from grayish pigmentation of skin in low concentrations to death in concentrations above 70% [15]. The definite diagnosis of methemoglobinemia is made by using co-oximetry [15].…”

“…Clinical manifestations of methemoglobinemia depend on blood concentration of Met-Hb and vary from grayish pigmentation of skin in low concentrations to death in concentrations above 70% [15]. The definite diagnosis of methemoglobinemia is made by using co-oximetry [15]. Methylene blue is the treatment of choice for methemoglobinemia and in both clinical and experimental studies it has been shown that methylene blue decreases Met-Hb concentration significantly [6,14] and relieves symptoms [7,14].…”

A 5-Month-Old Infant with Diffuse Cyanosis and No Other Symptoms

“…4 Methemoglobinemia is a blood disorder characterized by abnormal levels of oxidized hemoglobin in which the iron in the heme group is oxidized from the ferrous (Fe 2+ ) to the ferric (Fe 3+ ) state. 5 Therefore, methemoglobin has a greater oxygen affinity; consequently, the oxygen dissociation curve shifts to the left and less oxygen can be released in the tissues. For this reason, methemoglobin is useless as an oxygen carrier, leading to cyanosis.…”

Da escassez ao estresse do planeta: um século de mudanças no ciclo do nitrogênio

“…[52][53][54][55][56] O nitrato em excesso presente nas águas utilizadas para abastecimento público podem trazer graves problemas a saúde de crianças. 57,58 Por outro lado, o número de represas no Estado de São Paulo que estão eutrofizadas é facilmente constatável por simples observação. O excesso de nutrientes favorece o aparecimento de algas que podem alterar o odor ou gosto da água e podem produzir toxinas que inviabilizam o uso destas águas para o abastecimento humano ou de animais.…”