Impacto da vacinação contra varicela na redução da incidência da doença em crianças e adolescentes de Florianópolis (SC)

Abstract

Objective: To evaluate the impact of universal early childhood vaccination against varicella on the reduction of its incidence in a state capital in southern Brazil. Methods:Official epidemiologic surveillance data from the SINAN database for the 1997-2007 period were used to evaluate the impact of varicella vaccination targeting all children < 2 years of age in Florianópolis (the capital city of the state of Santa Catarina), Brazil, since 2002, thus comprising 5 years before and 6 years after the vaccination. Varicella incidence in Florianópolis was compared with the incidence in the rest of the state for four age groups (< 1, 1-4, 5-9, and 10-14 years).Results: Among the 135,311 cases of varicella in the state of Santa Catarina during the 1997-2007 period, 70% were children under 10 years of age. The effectiveness of varicella vaccine ranged from 27 to 38% among the age groups but reached statistical significance only for children 1-4 years old. Conclusion:The vaccine was effective in reducing varicella incidence in Florianópolis for children 1-4 years old.J Pediatr (Rio J). 2009;85(4):365-368: Varicella, vaccine, effectiveness.

Burden of varicella in Latin America and the Caribbean: findings from a systematic literature review

“…A seasonal pattern of infection was also observed, with incidences typically peaking during the winter and spring; this was noted in both tropical (Mexico) and temperate (Uruguay, Argentina, Brazil) countries [42]. The highest incidence of varicella was reported in children aged < 10 years [22, 30, 42].…”

“…In 2009, the incidence in Uruguay was 20/100,000 [23]. In the Florianópolis, after initiation of varicella vaccination targeting all children < 2 years old in 2002, there was a 75.5% reduction in incidence among the group of children aged 1–4 years; this contrasted with a rising incidence in this age group in the rest of the state, which had not implemented vaccination [30].…”

Impacto da vacina varicela nas taxas de internações relacionadas à varicela: revisão de dados mundiais

“…In Brazil, the first publication including data on the impact of the VV was a study comparing the incidence of varicella in children from Florianópolis - a city that implemented VV in the population under 2 years old in 2002 - and the remainder of the state of Santa Catarina 41. The study observed a 75.5% decrease in the incidence rate of the capital, compared with the rest of state, in children aged 1-4 years, and compared the pre- and post-vaccination period, but the study failed to present data on hospitalization rates.…”

<b>Perfil vacinal dos profissionais de enfermagem em hospital referência para doenças infecciosas de Fortaleza - Ceará</b> DOI: 10.4025/cienccuidsaude.v12i3.15052

“…Quanto à febre amarela, no estado do Ceará, não há ocorrência de casos confirmados e igualmente não é considerada área de risco para transmissão (16) . No entanto, embora este não seja considerado um estado endêmico da patologia, fazse indispensável à vacinação contra esta doença em trabalhadores que atuem em hospitais, devido à exposição.…”

“…Até o momento, a vacinação universal foi referida em um estudo realizado em Florianópolis, na qual apresenta as primeiras estimativas da efetividade da vacina contra a varicela na redução da incidência da doença para a faixa etária entre 1 e 4 anos com base em um programa de vacinação universal infantil precoce no Brasil. Contudo, seus resultados indicam uma redução da incidência compatível com aquela relatada nos Estados Unidos da América (16) .…”