Atresia biliar extra-hepática: métodos diagnósticos

Abstract

The referring of patients bearers of EHBA to centers of references in Brazil, is still made tardily, probably due to lack of enlightenment of the doctors of primary attention, allied to bureaucratic and technological difficulties. The experience in England in relation to the "Yellow Alert" program, allowed that the number of children referred to surgical treatment before the 60 days of life increased significantly. Among the complementary methods, the MR cholangiography, ultrasonography and hepatic biopsy should be used, depending on the technological resources of the diagnosis units.

Diagnostic value of anti-smooth muscle antibodies and liver enzymes in differentiation of extrahepatic biliary atresia and idiopathic neonatal hepatitis

“…EHBA must be managed operatively as soon as possible, while the preferred treatment of INH is medical. [ 27 28 29 ] Late referral of cholestatic neonates is one of the main problems of these patients, especially in developing countries. [ 30 ] In our study, the median age of neonates that refer with cholestasis was 54.66 ± 25.86 days (9-113 days).…”

Calcificação Distrófica Em Seio Maxilar De Paciente Pediátrico Com Transplante Hepático E Pigmentação Do Órgão Dental

“…Chronic liver disease may alter these functions, especially in the presence of a perinatal inflammatory process initiated in bile ducts, resulting in progressive fibrosclerosis and intra- and extrahepatic obstruction. 3 , 4 , 5 Hepatic transplantation is often the preferred therapy for a wide range of chronic liver diseases. 6 After transplantation, calcineurin inhibitors such as cyclosporine and tacrolimus are initiated, which dramatically increases the transplanted organ’s lifetime.…”

Ascorbic acid supplementation has a cytoprotective effect on secondary biliary cirrhosis: experimental study in young rats

“…Algumas doenças que causam colestase em recém-nascidos e bebês evoluem para doença hepática crônica com cirrose biliar, mais rapidamente do que as doenças colestáticas em adultos 5 . A atresia biliar é a causa mais importante de colestase nos primeiros 4 meses de vida, uma vez que sempre evolui para óbito se não tratada e é a principal indicação de transplante hepático na infância 3,6 . A ligadura e ressecção do ducto biliar comum em ratos adultos foi usada como modelo para colestase obstrutiva e cirrose biliar secundária.…”