Glasgow outcome scale at hospital discharge as a prognostic index in patients with severe traumatic brain injury

Oliveira, Rosmari Aparecida Rosa Almeida de; Araújo, Sebastião; Falcão, Antônio Luís Eiras; Soares, Silvia M.T.P.; Kosour, Carolina; Dragosavac, Desanka; Cintra, Eliane A.; Cardoso, Ana Paula Devite; Thiesen, Rosana A.

doi:10.1590/s0004-282x2012000800009

Cited by 14 publications

(15 citation statements)

References 29 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…An epidemic that affects mainly the young damages a country's future. 9 From 11 studies, 1,5,6,8,[10][11][12][13][14][15][16] car accidents were involved in 43% of TBI, as compared with motorbike (30%) and pedestrian (27%). Of the six studies 1,6,11,12,14,15 (n = 1,753) including a pedal bicycles category, car dropped slightly to 40%, while motorbike and pedestrian were both associated with 23% of TBI and pedal bike was related in 14% of TBI.…”

Section: Discussionmentioning

confidence: 99%

The Epidemiology of Traumatic Brain Injury Due to Traffic Accidents in Latin America: A Narrative Review

Dunne¹,

Quiñones-Ossa

Still

et al. 2020

JNRP

View full text Add to dashboard Cite

Objective Traumatic brain injuries (TBIs) are devastating injuries and represent a major cause of morbidity and mortality worldwide. Traffic accidents are one of the main causes, especially in low- and middle-income countries. The epidemiology of TBI due to road traffic in Latin America is not clearly documented. Methods A narrative review was conducted using PubMed, SCOPUS, and Google Scholar, looking for TBI studies in Latin America published between 2000 and 2018. Seventeen studies were found that met the inclusion and exclusion criteria. Results It was found that TBI due to road traffic accidents (RTAs) is more frequent in males between the ages of 15 and 35 years, and patients in motor vehicles accounted for most cases, followed by pedestrians, motorcyclists, and cyclists. Conclusion Road traffic accidents is a common cause of TBI in Latin America. More studies and registries are needed to properly document the epidemiological profiles of TBI related to RTAs.

show abstract

Section: Discussionmentioning

confidence: 99%

The Epidemiology of Traumatic Brain Injury Due to Traffic Accidents in Latin America: A Narrative Review

Dunne¹,

Quiñones-Ossa

Still

et al. 2020

JNRP

View full text Add to dashboard Cite

show abstract

“…18 Therefore, GOS measurement at the time of hospital discharge is a prognostic marker for clinical outcome at six months. 19 To present shortterm clinical outcome, the study also included LOS (Table 3). Table 3.…”

Section: Short-term Clinical Outcomementioning

confidence: 99%

Tigecycline reduced tumor necrosis factor alpha level and inhospital mortality in spontaneous supratentorial intracerebral hemorrhage

et al. 2016

View full text Add to dashboard Cite

Hasil: Didapatkan perbedaan bermakna pada proporsi subjek yang mengalami penurunan kadar TNF-α pada kelompok tigesiklin dibanding fosfomisin pada hari ke-7 pascabedah (62% vs 29%, p=0,022). Pengurangan edema pacsa operasi berbeda tidak bermakna pada kedua kelompok (86% vs 80%, p=0,580). Tigesiklin menunjukkan efektivitas klinis mengurangi luaran buruk (GOS ≤ 2 (20% vs 38% ; p=0,096; OR=0,41; NNT=6) dan inhospital mortality ( 17% vs 35%; p=0,083; OR=0,49; NNT=5). LOS ≥ 15 hari ( 40% vs 27%; p=0,243;OR=1,81; NNT=8). Kesimpulan: Tigesiklin memiliki kemampuan antiinflamasi dan neuroproteksi, serta memperbaiki luaran klinis pada PISS yang dilakukan evakuasi hematoma. ABSTRACT Background:The outcome of patients with spontaneous supratentorial intracerebral hemorrhage (SSICH) is unsatisfactory. Inflammatory response secondary to brain injury as well as those resulted from surgical procedure were considered responsible of this outcome. This study was intended to elucidate the anti-inflammatory activity of tigecycline by measuring TNF-α level and its neuroprotective effect as represented by inhospital mortality rate. Methods:Patients with SSICH who were prepared for hematoma evacuation were randomized to receive either tigecycline (n=35) or fosfomycine (n=37) as prophylactic antibiotic. TNF-α level was measured in all subjects before surgery and postoperatively on day-1 and day-7. A repeated brain CT Scan was performed on postoperative day-7. The Glasgow outcome scale (GOS) and length of stay (LOS) were recorded at the time of hospital discharge. Data were analyzed using Mann-Whitney and Chi square test. Relative clinical effectiveness was measured by calculating the number needed to treat (NNT).Results: There was a significant difference regarding the proportion of subject who had reduced TNF-α level on postoperative day-7 between the groups receiving tigecycline and fosfomycine (62% vs 29%, p=0.022). Decrease brain edema on CT control (86% vs 80%, p=0.580). Tigecycline administration showed a tendency of better clinical effectiveness in lowering inhospital mortality (17% vs 35%; p=0.083; OR=0.49; NNT=5) and worse clinical outcome / GOS ≤ 2 (20% vs 38% ; p=0.096; OR=0.41; NNT=6). LOS ≥ 15 hari ( 40% vs 27%; p=0.243; OR=1.81; NNT=8). Conclusion:Tigecycline showed anti-inflammatory and neuroprotective activities. These activities were associated with improved clinical outcome in patients with SSICH after hematoma evacuation.

show abstract

“…1,2 A large number of patients with TBI are admitted to intensive care units, but outcomes after one year are difficult to anticipate during the acute period.…”

Section: Introductionmentioning

confidence: 99%

“…5,6 Moreover, the GOSE also considers physical, social and cognitive outcomes. 2 Although the roles of GOS and GOSE in the prediction of TBI outcomes have not been completely proven, in general, they can be beneficial for predicting functional outcomes and as indicators for starting rehabilitation sooner which can, ultimately, reduce the cost of care. [7][8][9][10] Arterial blood gas demonstrates the acid-base balance of a patient.…”

Section: Introductionmentioning

confidence: 99%

Initial GCS and laboratory findings of patients with TBI are associated with the GOSE and mortality rate at one year

Paydar¹,

Bordbar²,

Taghipour³

et al. 2017

Int J Res Med Sci

View full text Add to dashboard Cite

Background: To evaluate the relationship between presenting Glasgow Coma Scale (GCS) or laboratory data of patients with TBI and Extended Glasgow Outcome Scale (GOSE) and final outcome (deceased, survived) at one year.Methods: 74 patients (59 males and 15 females; mean age ±SD of 40±19years) who presented with TBI were entered into the study, and their GCS and laboratory data were recorded. After one year, GOSE level and final outcome were evaluated with 11 yes/no questions obtained from the patients or their first-degree relatives.Results: The patients with lower GCS on admission or day six, significantly had lower GOSE. Moreover, the lower the GCS in the first week of admission, the poorer the final outcome. Among laboratory data, the base deficit (BD) level of -6 or worse on admission was an indicator of mortality at one year. Hypernatremia was the only laboratory factor which predicted poor GOSE after a year. Furthermore, patients with serum hypernatremia, hyperkalemia, or high PTT levels on the first week of admission had poor final outcome.Conclusions: Presenting GCS and metabolic derangements are reliable indicators of long-term outcome and GOSE at one year.

show abstract

Glasgow outcome scale at hospital discharge as a prognostic index in patients with severe traumatic brain injury

Cited by 14 publications

References 29 publications

The Epidemiology of Traumatic Brain Injury Due to Traffic Accidents in Latin America: A Narrative Review

The Epidemiology of Traumatic Brain Injury Due to Traffic Accidents in Latin America: A Narrative Review

Tigecycline reduced tumor necrosis factor alpha level and inhospital mortality in spontaneous supratentorial intracerebral hemorrhage

Initial GCS and laboratory findings of patients with TBI are associated with the GOSE and mortality rate at one year

Contact Info

Product

Resources

About