2009
DOI: 10.1590/s0004-282x2009000600027
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Supratentorial intraventricular schwannoma of the choroid plexus

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Cited by 17 publications
(4 citation statements)
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“…Etiopathogenesis of such a neoplasm within the cerebral ventricles is perplexing and, hence, several hypotheses have been introduced [ 3 7 ]: (1) growth from autonomic nerve cells inherent to choroid plexus or from nervi vasorum , a premise based on the identification of the former by Benedikt in 1874 and confirmed by Stöhr in 1922 [ 33 , 34 ] (also, the apparent attachment to choroid plexus supports this conjecture), (2) development from displaced neural crest cells which, in turn, may give rise to ectopic Schwann cells, and (3) neoplastic transformation of multipotent stem cells . Although no sole speculation may be sufficient to explain every single case—as different, nonexcluding mechanisms shall be involved—recent advances in the recognition of the so-called “neural stem cells” make the third assumption particularly attractive.…”
Section: Discussionmentioning
confidence: 99%
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“…Etiopathogenesis of such a neoplasm within the cerebral ventricles is perplexing and, hence, several hypotheses have been introduced [ 3 7 ]: (1) growth from autonomic nerve cells inherent to choroid plexus or from nervi vasorum , a premise based on the identification of the former by Benedikt in 1874 and confirmed by Stöhr in 1922 [ 33 , 34 ] (also, the apparent attachment to choroid plexus supports this conjecture), (2) development from displaced neural crest cells which, in turn, may give rise to ectopic Schwann cells, and (3) neoplastic transformation of multipotent stem cells . Although no sole speculation may be sufficient to explain every single case—as different, nonexcluding mechanisms shall be involved—recent advances in the recognition of the so-called “neural stem cells” make the third assumption particularly attractive.…”
Section: Discussionmentioning
confidence: 99%
“…Interestingly, it is well known that, in contrast to their peripheral counterpart, non-cranial nerve related neurilemmomas are more prone to diffusely express GFAP [ 3 ]. Unfortunately, just a couple of reports emphasise this difference and demonstrate it in their photographs [ 5 7 ]. In this regard, we share the opinion of Luo et al [ 4 ] stating that at least this subset of neurilemmomas arises from neoplastic transformation of subventricular pluripotent stem cells, hence preserving parental GFAP (+) immunophenotype which may in fact represent some kind of histogenetical imprinting .…”
Section: Discussionmentioning
confidence: 99%
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