2002
DOI: 10.1590/s0004-282x2002000600002
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Abstract: -The trail making test (TMT) pertains to a family of tests that tap the ability to alternate between cognitive categories. However, the value of the TMT as a localizing instrument remains elusive. Here we report the results of a functional magnetic resonance imaging (fMRI) study of a verbal adaptation of the TMT (vTMT). The vTMT takes advantage of the set-shifting properties of the TMT and, at the same time, minimizes the visuospatial and visuomotor components of the written TMT. Whole brain BOLD fMRI was perf… Show more

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Cited by 212 publications
(184 citation statements)
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References 33 publications
(28 reference statements)
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“…TMT B was related to activation in inferior dorsolateral prefrontal cortex, anterior cingulate, premotor cortex and intraparietal sulcus in fMRI studies 24 . Coherently, performance errors in TMT B have been reported as a feature with high positive predictive power for the presence of frontal lobe dysfunction 25 .…”
Section: Discussionmentioning
confidence: 87%
“…TMT B was related to activation in inferior dorsolateral prefrontal cortex, anterior cingulate, premotor cortex and intraparietal sulcus in fMRI studies 24 . Coherently, performance errors in TMT B have been reported as a feature with high positive predictive power for the presence of frontal lobe dysfunction 25 .…”
Section: Discussionmentioning
confidence: 87%
“…As both the Stroop interference condition (Gruber et al, 2002) and the NGA (Fallgatter et al, 2002) have been associated with ACC functioning and our two groups of patients differed regarding their mean NGA, an accompanying difference in Stroop interference performance is highly plausible. As the Stroop task was the only task we used that is thought to specifically involve the ACC, a missing effect in the other two testsFwhich have been shown to preferentially activate other frontal areas such as the dorsolateral prefrontal cortex or Broca's area (Gaillard et al, 2000;Moll et al, 2002)Fappears to be plausible as well.…”
Section: Discussionmentioning
confidence: 99%
“…The Trail Making Test (TMT) (Reitan, 1955;Reitan & Wolfson, 2001) is a brief, easily administered, and inexpensive screening tool consisting of two conditions: Trail Making Part A (TMT-A) and Trail Making Part B (TMT-B). TMT-B has been frequently used as an index of cognitive flexibility or set-shifting, an important aspect of executive attention control (Arbuthnott & Frank, 2000;Horton, 1979;Kortte, Horner, & Windham, 2002;Moll, Oliveira-Souza Rd, Moll, Bramati, & Andreiuolo, 2002). The TMT has been demonstrated to be sensitive to cognitive impairment in a range of agerelated clinical conditions, including Parkinson disease (Goldman, Baty, Buckles, Sahrmann, & Morris, 1998;Pillon et al, 1995), Alzheimer's disease (Chen et al, 2000(Chen et al, , 2001, and other dementias (Hestad, Aukrust, Ellertsen, & Klove, 1996;Heun, Papassotiropoulos, & Jennssen, 1998;Lunn et al, 1991;Paul et al, 2001;Selnes et al, 1991).…”
Section: Introductionmentioning
confidence: 99%