Sarcoma de Ewing epidural lombar primário: Relato de caso

Kadri, Paulo Abdo do Seixo; Mello, Paulo Mácio Porto de; Olivera, Jean Gonçalves de; Braga, Fernando Menezes

doi:10.1590/s0004-282x2002000100027

Cited by 8 publications

(2 citation statements)

References 23 publications

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“…Thoracolumbar spine is most commonly affected and cervical involvement is rare. On MRI, these lesions commonly appear isointense to muscle on T1weighted images, hyperintense on T2 weighted images and show moderate enhancement on contrast-enhanced T1 weighted images without bony involvement [14] [15]. These data had been found in our case.…”

Section: Discussionsupporting

confidence: 78%

Primary Intramedullary Ewing’s Sarcoma: A Case Report and Review of the Literature

Coulibaly¹,

Gana²,

Sogoba³

et al. 2015

CRCM

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Ewing's sarcoma, a group of primary neuroectodermal tumor (PNET), is an uncommon rare highly malignant tumor mostly affecting the bones of male patients, and accounts for approximately 10% of the primary malignant bone tumors, and occupies the second place after osteosarcoma in children's less than 20 years. Primary intramedullary Ewing's sarcoma is an extremely rare condition. Here, we present a case of a 16-year-old girl with progressive weakness of lower extremities, inability to walk, progressive low back pain, bilateral leg pain, paresthesia and urinary retention. Spinal MRI showed intramedullary abnormal signal focus from T11 to L3 vertebrae with moderate heterogeneous enhancement on T1 weighted sequences. After surgery, histological examination found a lot of small round-cell tumors with a high nuclear-cytoplasmic ratio, frequent mitoses and apoptotic nuclei suggesting a diagnosis of Ewing's sarcoma and confirmed by CD99 reactivity. She had undergone adjuvant chemotherapy and irradiation and was free of symptoms since 02 years. Within this single pure case of intramedullary Ewing's sarcoma, perhaps the 1st in the English literature, the authors described this extremely rare uncommon localization with a brief review of the literature.

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Section: Discussionsupporting

confidence: 78%

Primary Intramedullary Ewing’s Sarcoma: A Case Report and Review of the Literature

Coulibaly¹,

Gana²,

Sogoba³

et al. 2015

CRCM

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“…By now, 106 cases[1–57–912–141617192325–32363841–5052–5456–6266–6870717377–79818486–9092939597–113115116] of primary intraspinal EES/pPNET (extradural/intradural extramedullary lesions) and 29 cases[31118202228353740515255697172808283859194114] of primary intramedullary PNET (CNS-PNET) have been reported in the literature [Tables 1 and 2]. In some studies, neither intra- nor extramedullary location of the tumor was mentioned, so they were not included in any of the groups in our review (i.e.…”

Section: Results Of the Meta-analysismentioning

confidence: 99%

Primary spinal extradural Ewing′s sarcoma (primitive neuroectodermal tumor): Report of a case and meta-analysis of the reported cases in the literature

Saeedinia¹,

Nouri²,

Alimohammadi³

et al. 2012

Surg Neurol Int

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Background:Primary spinal primitive neuroectodermal tumors (PNET) and/or spinal extraskeletal Ewing's sarcoma family tumors (ESET) are rare lesions appearing in the spinal extradural space. One hundred forty-one primary spinal PNETs, including 29 intramedullary lesions, have been reported in the literature. Encountering a case of primary epidural EES/peripheral PNET (pPNET) in sacral level, which is the fifth one occurring at this level in the literature, we have tried to conduct a meta-analysis of the reported cases.Case Description:A 44-year-old lady with epidural EES/pPNET is reported here. She was once operated for L5/S1 herniated disc, which did not ameliorate her symptoms. The clinical, imaging, surgical, and histopathologic characteristics of our case are presented and wide search of the literature is also done. All the reports were level 3 or less evidences and most of the series had missing parts. 106 cases of primary intraspinal (extradural/extramedullary-intradural) EES/pPNET and 29 cases of primary intramedullary PNET (CNS-PNET) have been reported in the literature. The most common clinical presentation in both entities was muscle weakness proportionate to the tumor location. Distant metastasis occurred in 38 of 99 (38%) cases of primary intraspinal EES/pPNET, while the rate of metastasis was 48% in patients with PNETs occurring in the intramedullary region (P > 0.05). One-year survival rate of the patients who underwent chemo-radiation after total or subtotal resection was better than those who did not receive chemotherapy or radiotherapy, or did not have total or subtotal resection. However, this difference was not repeated in 2-year survival rate in any of the tumor groups.Conclusion:It seems that total or subtotal removal of the tumor and adjuvant chemo- and radiation therapy can improve the outcome in these patients.

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Epidural Tumors

Surgery of Spinal Tumors

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Sarcoma de Ewing epidural lombar primário: Relato de caso

Cited by 8 publications

References 23 publications

Primary Intramedullary Ewing’s Sarcoma: A Case Report and Review of the Literature

Primary Intramedullary Ewing’s Sarcoma: A Case Report and Review of the Literature

Primary spinal extradural Ewing′s sarcoma (primitive neuroectodermal tumor): Report of a case and meta-analysis of the reported cases in the literature

Epidural Tumors

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