Developmental milestones of vertically HIV infected and seroreverters children: follow up of 83 children

Bruck, Isac; Tahan, Tony Tannous; Cruz, Cristina Rodrigues; Martins, Luzilma Terezinha Flenik; Antoniuk, Sérgio Antônio; Rodrigues, Marcelo Masruha; Souza, Sílvia Mara de; Bruyn, Lais Regina De

doi:10.1590/s0004-282x2001000500007

Cited by 36 publications

(28 citation statements)

References 17 publications

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“…Among them, the central nervous system (CNS) is frequently affected, causing delays in neurodevelopment that can be one of the first symptoms of the disease [1][2][3][4][5][6]. Children with verticallytransmitted HIV can develop rapid or slow progressive psychoneuromotor development deceleration, which can begin as soon as six months of age.…”

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Neurological profile and neurodevelopment of 88 children infected with HIV and 84 seroreverter children followed from 1995 to 2002

Tahan¹,

Bruck²,

Burger³

et al. 2006

Braz J Infect Dis

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This study evaluated the degree of neurological compromise in HIV-infected children accompanied by the outpatient clinic of infectious diseases and pediatric neurology of the Clinical Hospital of the Federal University of Paraná (UFPR) starting in 1995. Long-term progressive prospective and cross sectional study of 88 children infected by HIV and 84 seroreverter children, using data from general neurological examinations, neuroimaging procedures (brain CT scan) and neurodevelopmental tests (CAT/CLAMS and DENVER I and II). Neurological and neurodevelopmental alterations were found in 82% of the HIV-infected patients and in 36% of the HIV-seroreverter group (P <0.01). In the CAT/ CLAMS test, the development quotient (DQ) of the HIV-infected group was significantly lower than that of the HIV-seroreverter group. CAT/CLAMS scores lower than 70 (mental deficiency) were found in 31% of the HIV-infected patients during the first year of life and in only 1% of the patients of the HIV-seroreverter group, demonstrating the validity of this screening test for precocious detection of alterations in the neurodevelopment of infected patients. The same occurred with the Denver I and II tests, as the HIV-infected group failed more frequently than the HIV-seroreverter group. Nine HIVinfected children presented altered brain CT scans; calcification of basal ganglia was the main finding (five cases). Encephalopathy due to HIV causes early arrest of neurodevelopment, which can be detected with screening tests during the first year of life.

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“…Children with verticallytransmitted HIV can develop rapid or slow progressive psychoneuromotor development deceleration, which can begin as soon as six months of age. Other children may have static encephalopathy [1][2][3][4][5][6].…”

mentioning

confidence: 99%

Neurological profile and neurodevelopment of 88 children infected with HIV and 84 seroreverter children followed from 1995 to 2002

Tahan¹,

Bruck²,

Burger³

et al. 2006

Braz J Infect Dis

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“…O teste é considerado de fácil execução e oferece um manual para treinamento e orientações quanto à sua utilização. Pode ser aplicado por vários profissionais da saúde e, por isso, é um dos testes mais utilizados na triagem de atrasos, inclusive em nosso país 22,[24][25][26][27][28][29][30][31][32][33] . Embora o teste não seja validado para nossa população, uma adaptação cultural não formal foi realizada a fim de facilitar a sua aplicação 24 .…”

Section: Síntese Dos Dadosunclassified

Early diagnosis of abnormal development of preterm newborns: assessment instruments

Santos¹,

Araujo²,

Porto³

2008

J Pediatr (Rio J)

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ResumoObjetivo: Revisar criticamente os instrumentos de avaliação mais utilizados na atualidade na literatura para triagem e identificação precoce de anormalidades no desenvolvimento em crianças. Fontes dos dados:Foi realizado um levantamento bibliográfico nas bases de dados no SciELO, plataforma CAPES, PubMed e Google Scholar, com os unitermos "prematuridade", "atraso no desenvolvimento", "paralisia cerebral", "diagnóstico precoce" e "testes de avaliação". Síntese dos dados:Foram listados 455 títulos, sendo selecionados para esta revisão 174 artigos com base em título, relevância temática e resumo. Apenas artigos originais, disponíveis em meio eletrônico, a partir de 1985, com informação sobre a construção, aplicabilidade e propriedades psicométricas dos testes foram usados. Sources: A search on SciELO, PubMed and Google Scholar was performed using the terms "prematurity," "developmental delay," "cerebral palsy," "early diagnosis" and "evaluation tests." Conclusões Summary of the findings:A total of 455 references were listed, and 174 studies were selected for this review based on title,

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“…It can be administered by several health professionals and, therefore, it is one of the tests most commonly used to screen developmental delays even in Brazil. 22,[24][25][26][27][28][29][30][31][32][33] Although the test has not been validated for our population, an informal cultural adaptation has been carried out to make its administration easier. 24 Another advantage is the wide age group reached by this test, which makes a long-term follow-up of child develop- resulting from visual and auditory stimuli or through the manifestation of motor landmarks.…”

Section: Summary Of the Findingsmentioning

confidence: 99%

Diagnóstico precoce de anormalidades no desenvolvimento em prematuros: instrumentos de avaliação

Santos

Araujo²,

Porto³

2008

J. Pediatr. (Rio J.)

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Objective: To review the literature regarding screening psychomotor tests for the early identification of developmental problems. Sources:A search on SciELO, PubMed and Google Scholar was performed using the terms "prematurity," "developmental delay," "cerebral palsy," "early diagnosis" and "evaluation tests." Summary of the findings:A total of 455 references were listed, and 174 studies were selected for this review based on title, relevance, and abstract. Only original and electronically available material, from 1985 forward, with information on design, applicability, and psychometric properties of those tests was included. Conclusions:Screening tests are important to speed the beginning of treatment measures in order to allow for better developmental outcome. Among the many tests that can be employed for this purpose, the DENVER II and the Alberta Infant Motor Scale are the most often used in Brazilian studies. The Movement Assessment of Infants is starting to be used in our country. Two other tests are recommended in the literature due to their high sensibility and specificity:the Test of Infant Motor Performance and the General Movements.J Pediatr (Rio J). 2008;84(4):289-299: Prematurity, motor delay, early diagnostic, screening tests.

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Developmental milestones of vertically HIV infected and seroreverters children: follow up of 83 children

Cited by 36 publications

References 17 publications

Neurological profile and neurodevelopment of 88 children infected with HIV and 84 seroreverter children followed from 1995 to 2002

Neurological profile and neurodevelopment of 88 children infected with HIV and 84 seroreverter children followed from 1995 to 2002

Early diagnosis of abnormal development of preterm newborns: assessment instruments

Diagnóstico precoce de anormalidades no desenvolvimento em prematuros: instrumentos de avaliação

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