Hormonal dysfunction in human reproduction and complex partial seizures

Abstract

We selected 85 CSF samples from patients, 26 of them with the active form of NCC, 17 with inactive form of NCC, and 42 with other neurological diseases. The selection was based on clinical, tomographic and CSF basis.It was observed that the inactive form of NCC presents an immunological profile similar to that of the group without NCC. The active form presents elevation of all specific immunoglobulins studied being that pattern heterogeneous in each class, being highest the participation of IgG, IgM, IgE and IgA in decrescent order.The highest values of mean optical density was observed in the cases with intraventricular cysts or signs of inflammation in the CSF and in the cases with multiple clinical manifestations.The diagnostic potential of each immunoenzymatic test was assayed. The ELISA IgG showed the highest value, with sensibility of 88.5% and specificity of 93.2%.The present stydy confirmed the importance of ELISA in the immunological diagnosis of NCC, particularly in the active forms.