1997
DOI: 10.1590/s0004-282x1997000100002
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Abstract: -The detection of IgE is technically difficult because of its reduced concentrations in serum, and even lower concentrations in cerebrospinal fluid (CSF). In the present investigation we studied 86 CSF samples using an immunoenzymatic method with an anti-IgE-alkaline phosphatase conjugate and a fluorigenic substrate. The samples were from three groups: A) 29 patients with neurocysticercosis (NC), B) 36 patients with different neurologic disorders (neurosyphilis, neurotuberculosis, meningitis, tumors, hemorrhag… Show more

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Cited by 7 publications
(6 citation statements)
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“…Most of these studies have reported proinflammatory states during symptomatic periods (defined by the mitogen- or antigen-driven secreted cytokine patterns by peripheral blood mononuclear cells or cells from the cerebrospinal fluid) and asymptomatic chronic disease states associated with regulatory (or an ‘anti-inflammatory’) milieu [1720]. Based on these observations, investigators have suggested that acute symptomatic individuals with NCC have a Th1-type profile in the peripheral blood, whereas asymptomatic individuals (with live parasites or calcified lesions) have predominantly Th2 responses to parasite antigens [21].…”
Section: Nature Of Inflammation In Nccmentioning
confidence: 99%
“…Most of these studies have reported proinflammatory states during symptomatic periods (defined by the mitogen- or antigen-driven secreted cytokine patterns by peripheral blood mononuclear cells or cells from the cerebrospinal fluid) and asymptomatic chronic disease states associated with regulatory (or an ‘anti-inflammatory’) milieu [1720]. Based on these observations, investigators have suggested that acute symptomatic individuals with NCC have a Th1-type profile in the peripheral blood, whereas asymptomatic individuals (with live parasites or calcified lesions) have predominantly Th2 responses to parasite antigens [21].…”
Section: Nature Of Inflammation In Nccmentioning
confidence: 99%
“…Some authors have reported IgG, IgM, IgA, IgE and IgD antibodies in CSF and/or serum from patients with NC, without correlation between antibody class and clinical aspect of the disease 13,15,16 . In parasitic infections, including the teniasis-cysticercosis complex, the level of total IgE can be high, many times without the identification of the specificity of the antibody 17,18 .…”
mentioning
confidence: 99%
“…There are only few reports about the immune response in different evolutionary stages of NC 4 . The level of total IgE has been determined by different methods in parasitic infections, including NC 10,14,19,21 . OSTROSKY-ZEICHNER et al 15 , reported that total IgE levels determined by radioimmunoassay were higher than control in 59% of CSF samples from patients with NC.…”
Section: Discussionmentioning
confidence: 99%
“…Some authors have reported specific IgG, IgM, IgA and IgE antibodies in CSF and/or serum from patients with NC, without a correlation between antibody class and clinical aspect of the disease 3,5,6,12 . In parasitic infections, including the teniasis-cysticercosis complex, the level of total IgE can be high, many times without the identification of the specificity of the antibody 14,19 .…”
Section: Introductionmentioning
confidence: 99%