1995
DOI: 10.1590/s0004-282x1995000200006
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Abstract: SUMMARY -The main objective of this retrospective review of clinical and cerebrospinal fluid (CSF) data from 41 patients with intracranial tumors diagnosed between 1975 and 1989, is to report the role that the finding of neoplastic cells in CSF plays, specially when cerebral CT-scanning and MRI were not currently done. Another objective is to study the CSF proteic abnormalities in cerebral tumors. CSF cell count, cytomorphologic pictures obtained after sedimentation and protein findings are described. Tumor ce… Show more

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Cited by 8 publications
(9 citation statements)
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“…The diagnosis of the involvement of the meninges by extraneural cancer, leukemia cells, lymphomas and CNS primary tumors is based on cytological confirmation, either through CSF cytology or biopsy of leptomeninge 13 . The rate of positive CSF cytology found in our lab (24%) is a mean value compared to rates reported 12,14,15 , and is in accordance with some studies 14,16 . However, the positivity rate of detecting malignant cells in the CSF varies in the literature and is assumed to depend on several factors such as histological confirmation, local of CSF collection, and CSF processing methodology used for cells concentration as sedimentation chambers or cytospin [17][18][19] .…”
Section: Discussionsupporting
confidence: 92%
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“…The diagnosis of the involvement of the meninges by extraneural cancer, leukemia cells, lymphomas and CNS primary tumors is based on cytological confirmation, either through CSF cytology or biopsy of leptomeninge 13 . The rate of positive CSF cytology found in our lab (24%) is a mean value compared to rates reported 12,14,15 , and is in accordance with some studies 14,16 . However, the positivity rate of detecting malignant cells in the CSF varies in the literature and is assumed to depend on several factors such as histological confirmation, local of CSF collection, and CSF processing methodology used for cells concentration as sedimentation chambers or cytospin [17][18][19] .…”
Section: Discussionsupporting
confidence: 92%
“…our data showed that total CSF cell count was greater in the group with malignant cells than the group without malignant cells, consisting predominantly of lymphocytes and monocytes and in some cases neutrophils supporting reports from other studies 15,16 . Furthermore, other studies report an increase in total CSF cell count in 33 to 79% of cases studied of approximately 68 cells/ mm³, ranging from 18 to 685 cells/mm³.…”
Section: Grünwald/giensa Stain 1000x) the Cell Borders Are Irregulsupporting
confidence: 92%
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“…Primary cerebral tumors that exfoliated cells to the CSF were all located adjacent to the ventricle. In contrast, cells from tumors deeply localized in cerebral parenchyma are more difficult to find in the CSF [63][64][65][66][67][68].…”
Section: Carcinomatous Meningitismentioning
confidence: 99%