HTLV-I associated myelopathy in salvador (northeastern Brazil)

Meireles, Ana Célia Maia; Moreira, Edson Duarte; Moreno-Carvalho, Otávio A.; Badaró, Roberto; Melo, Aílton

doi:10.1590/s0004-282x1992000200010

Cited by 14 publications

(1 citation statement)

References 8 publications

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“…The present case agrees with the age and gender most frequently affected by HTLV [18,19] and has occurred in an area of high prevalence of this infection [18]. In view of the clinical evolution of the patient, it is likely that she already presented Arnold-Chiari syndrome and syringomyelia at the time of surgery.…”

Section: Discussionsupporting

confidence: 86%

Association of HTLV-I with Arnold Chiari syndrome and syringomyelia

Viana¹,

Neto

Furtado

et al. 2008

Braz J Infect Dis

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HTLV-I is associated with a broad spectrum of manifestations, including tropical spastic paraparesis and adult T-cell leukemia/lymphoma. Arnold Chiari syndrome is a condition characterized by herniation of the cerebellar tonsils through the foramen magnum. This condition should be suspected in all patients with headache and impaired motor coordination. Syringomyelia is a developmental anomaly that leads to the formation of an intramedullary cavity. Its clinical presentation is classically characterized by syringomyelic dissociation of sensation, with suspended distribution in the proximal portion of the trunk and upper limbs and preservation in other regions. We report here a case of association of the three diseases, which is rare in clinical practice, illustrating the difficulty in the diagnosis and therapeutic management of these conditions.

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Section: Discussionsupporting

confidence: 86%

Association of HTLV-I with Arnold Chiari syndrome and syringomyelia

Viana¹,

Neto

Furtado

et al. 2008

Braz J Infect Dis

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Human T cell lymphotropic viruses (HTLV-I/II) in South America: Should it be a public health concern?

2002

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Human T lymphotropic virus type I (HTLV-I) infection in neurological patients in Salvador, Bahia, Brazil

Gomes

Melo

Proietti

et al. 1999

Journal of the Neurological Sciences

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HTLV-I infection represents a major health concern in endemic areas throughout the world, such as Salvador, the main city of Bahia State, with socio-demographic characteristics similar to sub-Saharan African cities, located in the Northeast of Brazil. In order to provide an estimate of the frequency distribution, and range of neurological manifestations potentially related to HTLV-I infection in this city, we conducted a cross-sectional clinical-epidemiological study to determine the prevalence of this infection in patients with neurological diseases. Patients exhibiting vascular diseases, tumoral diseases or trauma were excluded. Over a period of 16 months, we studied 322 consecutive patients with chronic neurological diseases, who attended the neurological clinics of two major hospitals in Salvador. Overall, the prevalence of HTLV-I infection among the patients was 20.9% (67/320). However, the prevalence among the 104 patients with chronic myelopathy was 50.0% (52/104). It was observed that the major prevalence of HTLV-I was between the ages of 40 and 60 years with a female predominance. Our data indicate that, in Salvador city, HTLV-I is associated with chronic myelopathies or myeloneuropathies, which seem to be the only neurological diseases associated with HTLV-I.

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HTLV-I associated myelopathy in salvador (northeastern Brazil)

Cited by 14 publications

References 8 publications

Association of HTLV-I with Arnold Chiari syndrome and syringomyelia

Association of HTLV-I with Arnold Chiari syndrome and syringomyelia

Human T cell lymphotropic viruses (HTLV-I/II) in South America: Should it be a public health concern?

Human T lymphotropic virus type I (HTLV-I) infection in neurological patients in Salvador, Bahia, Brazil

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