Neurocysticercosis an epidemiological survey in two small rural communities

Arruda, Walter O.; Camargo, Natal Jataí de; Coelho, Rosana C.

doi:10.1590/s0004-282x1990000400004

Cited by 24 publications

(19 citation statements)

References 18 publications

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“…Serological diagnosis of CC/NCC with EITB was performed in 16 studies, and the proportion ranged among 0% [38] and 39.5% [30]. Thirteen studies associated to neuroimaging or EITB other ascertainment methods for the diagnosis of CC/NCC, such as serum AbELISA, serum AgELISA, CSF AbELISA, serum ELISA/serum immunofluorescence assay, or CT/CSF test/surgery [39], with proportions ranging from 0% [38] to 41.9% [40].…”

Section: Resultsmentioning

confidence: 99%

Epilepsy and Neurocysticercosis in Latin America: A Systematic Review and Meta-analysis

et al. 2013

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BackgroundThe difference in epilepsy burden existing among populations in tropical regions has been attributed to many factors, including the distribution of infectious diseases with neurologic sequels. To define the burden of epilepsy in Latin American Countries (LAC) and to investigate the strength of association with neurocysticercosis (NCC), considered one of the leading causes of epilepsy, we performed a systematic review and meta-analysis of the literature.MethodologyStudies published until 2012 were selected applying predefined inclusion criteria. Lifetime epilepsy (LTE) prevalence, active epilepsy (AE) prevalence, incidence, mortality, treatment gap (TG) and NCC proportion among people with epilepsy (PWE) were extracted. Median values were obtained for each estimate using random effects meta-analysis. The impact of NCC prevalence on epilepsy estimates was determined using meta-regression models. To assess the association between NCC and epilepsy, a further meta-analysis was performed on case-control studies.Principal findingsThe median LTE prevalence was 15.8/1,000 (95% CI 13.5–18.3), the median AE prevalence was 10.7/1,000 (95% CI 8.4–13.2), the median incidence was 138.2/100,000 (95% CI 83.6–206.4), the overall standardized mortality ratio was 1.4 (95% CI 0.01–6.1) and the overall estimated TG was 60.6% (95% CI 45.3–74.9). The median NCC proportion among PWE was 32.3% (95% CI 26.0–39.0). Higher TG and NCC estimates were associated with higher epilepsy prevalence. The association between NCC and epilepsy was significant (p<0.001) with a common odds ratio of 2.8 (95% CI 1.9–4.0).SignificanceA high burden of epilepsy and of NCC in LAC and a consistent association between these two diseases were pointed out. Furthermore, NCC prevalence and TG were identified as important factors influencing epilepsy prevalence to be considered in prevention and intervention strategies.

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Section: Resultsmentioning

confidence: 99%

Epilepsy and Neurocysticercosis in Latin America: A Systematic Review and Meta-analysis

et al. 2013

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“…O mais simples deles é o exame parasitológico de fezes, permitindo a identificação de ovos de tênia nos indivíduos suspeitos de estarem infectados e infectando o meio em que vivem 2 . O exame de líquido céfalo-raquidiano, imprescindível em muitos casos para uma segura comprovação diagnóstica, assim como para fornecer evidências de atividade de NC, poderá exibir simultaneamente hipercitose com presença de eosinófilos e positividade de reações imunológicas específicas, como da reação de fixação de complemento 13 .…”

Section: Discussionunclassified

Neurocisticercose em pacientes internados por epilepsia no Hospital Regional de Chapecó região oeste do Estado de Santa Catarina

Trevisol-Bittencourt

Silva

Figueredo³

1998

Arq. Neuro-Psiquiatr.

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RESUMO -Neurocisticercose é condição provocada pela infecção do sistema nervoso pelo Cysticercus cellulosae, a forma larvária da Taenia solium. Ela é, muito provavelmente, a principal responsável pela elevada prevalência de epilepsia no Brasil. Em diversas áreas do país, possui um caráter endêmico, gerando grande dispêndio financeiro para um enfrentamento das diversas complicações neurológicas relacionadas a ela. Sabe-se que por suas peculariedades sócio-econômicas, com suinocultura disseminada, a região sul do Brasil, é considerada pelo ministério da Saúde como uma área de alto risco. Para averiguar sua importância entre nós, um estudo, considerando internações por epilepsia e sua etiologia, foi realizado na cidade de Chapecó, principal cidade do oeste de Santa Catarina. O período coberto pela investigação foi de 1995, entrada em funcionamento de tomógrafo computadorizado no Hospital Regional daquela cidade, até o mês de novembro de 1996. Uma expressiva prevalência de neurocisticercose, aproximada de 24%, foi observada entre os indivíduos internados pelo diagnóstico de epilepsia. Algo em torno de 40% dos infectados apresentava lesões em sua fase ativa, sugerindo uma aquisição recente. Nossos dados sugerem que a despeito desta região sediar agro-indústrias de projeção internacional, a cisticercose grassa endemicamente na área. Um controle deste flagelo terceiro mundista poderia ser obtido com a difusão de mensagens educativas, em linguajar apropriado, para uma sensibilização de toda a população vivendo naquela região. Além disso, todos aqueles indivíduos envolvidos em suinocultura, independentemente de como seja esta classificada, deveriam ser objeto de atenção especial. PALAVRAS-CHAVES: neurocisticercose, epilepsia, suinocultura. Prevalence of neurocysticercosis among epileptic in-patients in the west of Santa Catarina -southern BrazilABSTRACT -Neurocysticercosis (NC) is an endemic condition in several areas of Brazil. It is most likely the major responsible for the high prevalence of epilepsy in our country, estimated in 1-2% of general population. We performed a study to evaluate NC as aetiology of epilepsy in the west of Santa Catarina. This state belong to southern Brazil and it has a very developed economy. However, due the widespread swine farming in the west district, many of them without any sanitary control, the national health authorities have considered all this area at risk to NC. The study was carried out in Chapecó, the main town in that region, where CT Scan service was started in 1995. All patients put on hospital care due epileptic seizures in 1995-96 were considered. Febrile convulsions were excluded of the sample. We found a very expressive prevalence rate of NC among patients suffering from epilepsy. Roughly 24% of these patients, showed unequivocal tomography evidences for the diagnosis of NC. Our data suggest cysticercosis as a real endemic trouble in the area and, overdosis of information in proper language, diffuse to the whole population, seems to be the only remedy to fight against it....

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“…Its diagnosis is difficult, specially in non-endemic regions or regions lacking specialized laboratory facilities 1 . As quoted by Arruda et al 2 , neurocysticercosis is relatively rare in Brazilian States of North and Northeast.…”

Section: Classification Of Findings According To Kramer Et Al" and Mamentioning

confidence: 85%

Cerebral cysticercosis in Campina Grande, Paraíba - northern Brazil: computerized tomography diagnosis importance

Coêlho

1996

Arq. Neuro-Psiquiatr.

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-Neurocysticercosis is the infection of the central nervous system by the larval form of Taenia solium , the Cysticercus cellulosae. We studied 4011 computerized tomographies performed in TomoHPI Radioimaging Service, Hospital Pedro I, Campina Grande PB, Northern Brazil, since its installation on August 1993 to July 1995. 41 patients were diagnosed as having Cysticercus cerebral infestation, corresponding to an incidence of 1.02%. No cases were related in Campina Grande PB during 1991 according to hospitalizations under prospective payment rates. After this radioimaging service installation, we observed 1.86 cases per month. We conclude that Campina Grande has to be included as an endemic area of neurocysticercosis, needing health service measures to cease the cycle Taenia-Cysticercus, the only way to get rid of such a serious problem.

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Neurocysticercosis an epidemiological survey in two small rural communities

Cited by 24 publications

References 18 publications

Epilepsy and Neurocysticercosis in Latin America: A Systematic Review and Meta-analysis

Epilepsy and Neurocysticercosis in Latin America: A Systematic Review and Meta-analysis

Neurocisticercose em pacientes internados por epilepsia no Hospital Regional de Chapecó região oeste do Estado de Santa Catarina

Cerebral cysticercosis in Campina Grande, Paraíba - northern Brazil: computerized tomography diagnosis importance

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