Esclerose múltipla: estudo clínico e patológico de um caso

Abstract

We present a case with diagnosis of multiple sclerosis done on clinical criteria and proved by autopsy. The morphological aspects of the lesions are well known and often related in the literature. Our objective is to describe the first necropsy among 30500 done at Santa Casa de São Paulo in a patient with the disease. The morphological aspects in the CNS with the characteristic plaques in different grades of activity and the detection of immunoglobulins in these plaques confirm the pathogenic hypothesis about a disease immunologically mediated.

Professor Emeritus Charles Peter Tilbery [1944-2020]

“…Studies on specific aspects of MS, from its pathology to its immunology, epidemiology, multidisciplinary approach, and treatment 8,9,10,11,12,13,14,15,16,17,18 . Collaborative studies on the prevalence of MS in the city of São Paulo 19,20 .…”