2010
DOI: 10.1590/s0004-28032010000400013
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Abstract: -Context -The western dietary pattern is characterized by a high calorie intake with a high proportion of simple sugars.This diet is associated with comorbidities such as hepatic fat deposition and is possibly related to non-alcoholic fatty liver disease.Objective -To evaluate the capacity of a hyperglucidic diet to induce steatosis in adult male Wistar rats. After the administration of a carbohydrate-rich diet, we also evaluated the presence of hepatic and cardiac steatosis and the levels of intrinsic antioxi… Show more

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Cited by 4 publications
(10 citation statements)
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References 27 publications
(24 reference statements)
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“…The high liver weight of NC-fed rats may be an indicative of hepatic fat deposition due to high levels of carbohydrate in this diet. Similarly, it was previously reported that a carbohydrate-rich diet induced hepatic fat deposition 72 .…”
Section: Discussionmentioning
confidence: 59%
“…The high liver weight of NC-fed rats may be an indicative of hepatic fat deposition due to high levels of carbohydrate in this diet. Similarly, it was previously reported that a carbohydrate-rich diet induced hepatic fat deposition 72 .…”
Section: Discussionmentioning
confidence: 59%
“…It was found in other studies (34)(35)(36)(37)(38), high-carbohydrate diet caused to increase of adipose tissue and hepatic steatosis (39).…”
mentioning
confidence: 70%
“…Also, it was determined that high-carbohydrate diet increased hepatic fat synthesis, caused to the accumulation of triglyceride in the liver, rise of ALT, AST levels, and caused mitochondrial dysfunction in adipose tissue (31)(32)(33)(34)(35)(36)(37)(38).…”
mentioning
confidence: 99%
“…NAFLD with hepatic steatosis (HS) was induced in 36 rats of the experimental groups (E) by offering a high carbohydrate (70% sucrose) diet for 21 days, the induction phase, as previously reported. 25 Experimental NAFLD with HS is often induced with choline- and/or methionine-deficient diets, 26 or alternatively a fructose-rich diet. The high carbohydrate diet was chosen because it more accurately reproduces a so-called western diet than the other options.…”
Section: Methodsmentioning
confidence: 99%
“…The high carbohydrate diet was chosen because it more accurately reproduces a so-called western diet than the other options. 23 , 25 …”
Section: Methodsmentioning
confidence: 99%