Decrease in prevalence of Helicobacter pylori infection during a 10-year period in Brazilian children

Kawakami, Elisabete; Machado, Rodrigo Strehl; Ogata, Silvio Kazuo; Langner, Marini

doi:10.1590/s0004-28032008000200011

Cited by 53 publications

(40 citation statements)

References 20 publications

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“…This finding is in line with the current global trend of decreasing prevalence of H. pylori found by previous studies (3,12,13). No significant association was found between H. pylori infection and gender, but higher frequency of infection was observed among men in the current study.…”

Section: Discussionsupporting

confidence: 92%

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Proportion of Helicobacter pylori Among Dyspeptic Patients Detected by Molecular Methods in a Teaching Hospital in Sri Lanka

Ubhayawardana¹,

Weerasekera

Weerasekera³

et al. 2015

Int J Enteric Pathog

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Background: Infection with Helicobacter pylori is considered as a major cause of chronic gastritis, peptic ulcer disease and gastric cancer. More than half of the world's population is infected with H. pylori. In Sri Lanka various groups have reported a prevalence ranging from 3% to 70% over the last decade. Objectives: The aim of this study was to determine the current proportion of H. pylori and risk factors for H. pylori infections. Patients and Methods:The study was a cross sectional, descriptive study in which 100 dyspeptic patients who were required to undergo endoscopy examination were included. The study was carried out at a Teaching Hospital in Sri Lanka. In-house urease test and PCR amplification of the glmM gene of H. pylori was performed to diagnose H. pylori infection. A questionnaire was filled to collect sociodemographic data from the dyspeptic patients. Results: Eighteen dyspeptic patients were positive for H. pylori by both in-house CLO (Campylobacter-like organism test) test and polymerase chain reaction (PCR). Ten of cases were male (18%) while eight were female (17%). There was no association between the demographic factors and risk of H. pylori infection. Conclusions: The proportion of H. pylori infections was found to be 18% in the study population. There was no significant association with H. pylori and the studied demographic factors.

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Section: Discussionsupporting

confidence: 92%

“…Epidemiological studies from different countries have shown a decline in the prevalence of H. pylori infection with a significant variability among different ethnicities (3,4). The lowest prevalence rates were reported in developed countries (4,5).…”

Section: Introductionmentioning

confidence: 99%

Proportion of Helicobacter pylori Among Dyspeptic Patients Detected by Molecular Methods in a Teaching Hospital in Sri Lanka

Ubhayawardana¹,

Weerasekera

Weerasekera³

et al. 2015

Int J Enteric Pathog

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“…In populations with precarious SES, resident in urban and rural areas, the prevalence of infection may reach 70% of children at 5 years of age, reaching over 80% of individuals after the age of 20. Moreover, the improvement in the population's living conditions, characterized by higher household income, higher level of education and adequate health services, provides an impact on the prevalence of H pylori infection, with a drop in the prevalence of H pylori infection (1,32,103,108,138,170,183,202,212) .…”

Section: Group 5 Epidemiology Of Infection and Proposals For Action mentioning

confidence: 99%

3rd BRAZILIAN CONSENSUS ON Helicobacter pylori

Coelho

Maguinilk

Zaterka³

et al. 2013

Arq. Gastroenterol.

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Significant progress has been obtained since the Second Brazilian Consensus Conference on Helicobacter pylori Infection held in 2004, in São Paulo, SP, Brazil, and justify a third meeting to establish updated guidelines on the current management of H. pylori infection. The Third Brazilian Consensus Conference on H pylori Infection was organized by the Brazilian Nucleus for the Study of Helicobacter, a Department of the Brazilian Federation of Gastroenterology and took place on April 12-15, 2011, in Bento Gonçalves, RS, Brazil. Thirty-one delegates coming from the five Brazilian regions and one international guest, including gastroenterologists, pathologists, epidemiologists, and pediatricians undertook the meeting. The participants were allocated in one of the five main topics of the meeting: H pylori, functional dyspepsia and diagnosis; H pylori and gastric cancer; H pylori and other associated disorders; H pylori treatment and retreatment; and, epidemiology of H pylori infection in Brazil. The results of each subgroup were submitted to a final consensus voting to all participants. Relevant data were presented, and the quality of evidence, strength of recommendation, and level of consensus were graded. Seventy per cent and more votes were considered as acceptance for the final statement. This article presents the main recommendations and conclusions to guide Brazilian doctors involved in the management of H pylori infection.

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“…Although infection rates are decreasing in pediatric populations from different regions, with prevalence ranging from less than 10% to 28% (16,17,18,21,27) , H. pylori still plays an important role in the pathogenesis of peptic ulcer disease, gastric adenocarcinoma and gastric mucosaassociated lymphoid tissue lymphoma (2) -diseases that carry high morbidity and mortality rates. H. pylori infection is acquired predominantly in childhood (18,31) .…”

Section: Introductionmentioning

confidence: 99%

Prevalence of Infection With Caga-Positive Helicobacter Pylori Strains Among Children and Adolescents in Southern Brazil

Oliveira

Ferreira

Camerin³

et al. 2014

Arq. Gastroenterol.

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-Context -Helicobacter pylori (H. pylori) has a worldwide distribution, but the prevalence of infection, virulence factors, and clinical presentation vary widely according to the studied population. In Brazil, a continental country composed of several ethnicities and cultural habits, the behavior of infection also appears to vary, as many other studies have shown. Objective -Describe the prevalence of infection with cagA-positive H. pylori strains in a group of children and adolescents who underwent esophagogastroduodenoscopy in Porto Alegre, Rio Grande do Sul. Methods -Fifty-four gastric biopsy specimens of children and adolescents with H. pylori infection demonstrated by histology, urease test and molecular analysis were tested for the presence of cagA-positive H. pylori strains by the polymerase chain reaction method. Results -The prevalence of cagA-positive H. pylori was 29.6% (95% confidence interval, 18 to 43.6%). There were no statistically significant differences in clinical or demographic characteristics or in the endoscopic and histological features of patients infected with cagA-positive strains as compared with those infected by cagA-negative strains. Conclusions -The study showed a low prevalence of infection with cagA-positive H. pylori strains among children and adolescents who underwent EGD in southern Brazil, in comparison to studies conducted with children from other regions of Brazil. There was no association between the presence of cagA-positive strains and more severe clinical presentations in the studied sample.

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Decrease in prevalence of Helicobacter pylori infection during a 10-year period in Brazilian children

Cited by 53 publications

References 20 publications

Proportion of Helicobacter pylori Among Dyspeptic Patients Detected by Molecular Methods in a Teaching Hospital in Sri Lanka

Proportion of Helicobacter pylori Among Dyspeptic Patients Detected by Molecular Methods in a Teaching Hospital in Sri Lanka

3rd BRAZILIAN CONSENSUS ON Helicobacter pylori

Prevalence of Infection With Caga-Positive Helicobacter Pylori Strains Among Children and Adolescents in Southern Brazil

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