Cromoendoscopia com azul de metileno para diagnóstico de esôfago de Barrett

Saporiti, M.; Souza, Raquel Canzi de Almada e; Pisani, Júlio César; Amarante, Heda Maria Barska dos Santos; Carmes, Eliane Ribeiro; Sakamoto, Danielle Giacometti

doi:10.1590/s0004-28032003000300002

Cited by 7 publications

(1 citation statement)

References 15 publications

(83 reference statements)

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“…Nesses estudos também não foi comprovado o papel da coloração com azul de metileno para melhor avaliar as áreas de displasia de alto grau ou adenocarcinoma. O estudo de SAPORITI et al (11) , publicado neste número dos ARQUIVOS de GASTROEN-TEROLOGIA, mostrou que o emprego da cromoscopia com azul de metileno aumenta significativamente o tempo do exame endoscópico, além de não apresentar vantagens para o diagnóstico do EB.…”

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Esôfago de Barrett: novos métodos diagnósticos

Cecconello

Szachnowicz

2003

Arq. Gastroenterol.

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Esôfago de Barrett: novos métodos diagnósticos

Cecconello

Szachnowicz

2003

Arq. Gastroenterol.

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A meta-analysis of randomized controlled trials comparing methylene blue-directed biopsies with random biopsies in the surveillance of Barrett’s esophagus

Admad

Ahmed

2010

Esophagus

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A meta-analysis of randomized controlled trials comparing methylene blue-directed biopsies with random biopsies in the surveillance of Barrett's esophagus Abstract This study was designed to examine the shortfalls of methylene blue-directed biopsies (MBDB) and conventional random biopsies (RB) in the surveillance of Barrett's esophagus. A Cochrane and Medline search was performed, and fi ve randomized controlled trials (RCTs) comprising 213 patients were selected for the meta-analysis. Random biopsies failed to spot specialized intestinal metaplasia (SIM) in a signifi cantly higher number of patients than MBDB (risk ratio, 0.724; confi dence interval, 0.552-0.950). The rate of underdiagnosis of dysplasia was comparable between the two techniques (risk ratio, 0.766; confi dence interval, 0.273-2.147). More biopsies were obtained using the RB technique, and a signifi cantly higher number of biopsies was reported as normal in comparison to MBDB (P = 0.014). The use of endoscopic staining was associated with prolongation of the procedure time (P = 0.009). It was concluded that SIM is overlooked more often in conventional biopsy techniques, but the incidence of undetected dysplasia is comparable using both methods. The routine use of methylene blue in the surveillance of Barrett's esophagus seems to be unnecessary.

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Toward better imaging of Barrett's esophagus—see more, biopsy less!

Bansal

2006

Gastrointestinal Endoscopy

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Cromoendoscopia com azul de metileno para diagnóstico de esôfago de Barrett

Abstract: We concluded that methylene blue chromoendoscopy offered no advantage over the conventional method in the diagnosis of Barrett's esophagus.

Cited by 7 publications

References 15 publications

Esôfago de Barrett: novos métodos diagnósticos

Esôfago de Barrett: novos métodos diagnósticos

A meta-analysis of randomized controlled trials comparing methylene blue-directed biopsies with random biopsies in the surveillance of Barrett’s esophagus

Toward better imaging of Barrett's esophagus—see more, biopsy less!

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