Recurrent and de novo non-alcoholic steatohepatitis following orthotopic liver transplantation

Abstract

-Background -Non-alcoholic steatohepatitis was coined in 1980 to

Panniculitis and liver disease (hepatic Weber Christian disease)

“…There are some possible similarities between chronic HIV-1 and HCV infections: (1) both viruses are detected in plasma in the presence of specific antibodies, i.e. virusantibody complexes are formed [2,4]; (2) the erythrocytes CR1 are diminished in both infections suggesting 'consumpconsumption' due to excessive binding of immune complexes [5,6] and (3) relapses occur even when the viral loads in plasma have been reduced to undetectable levels, indicating that plasma levels are poor indicators of persistent viral replication. Using in situ RT-PCR on blood smears, Lotz et al have suggested that HCV may be found associated to erythrocytes in chronically infected patients, thus erythrocyte HCV might represent an unrecognized pool of viruses indicating ongoing infection [7].…”