volume 58, issue 1, P55-60 2021
DOI: 10.1590/s0004-2803.202100000-10
View full text
Ronaldo Eliezer MAMELLI, Aledson Vitor FELIPE, Tiago Donizetti SILVA, Vanessa HINZ, Nora Manoukian FORONES

Abstract: ABSTRACT BACKGROUND: Colorectal cancer is the third most common neoplasm in the world. Methylation of tumor related genes in CpG islands can cause gene silencing and been involved in the development of cancer. The potential role of DKK2 as a biomarker for early diagnosis of colorectal cancer remains unclear. OBJECTIVE: The aim of the study was to evaluate the profile of methylation and RNAm expression of DKK2 as potential predictors of colorectal cancer diagnosis and prognosis. METHODS: Expression of mRN…

Expand abstract