Síndrome de Cogan: relato de caso

Medeiros, Fabrício Witzel de; Altieri, Rosana Aparecida Soares; Souza, Murilo Barreto; Milani, José Antonio de Almeida; Alves, Mílton Ruiz

doi:10.1590/s0004-27492005000600026

Cited by 1 publication

(1 citation statement)

References 9 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Other than VKHS, immunomediated sensorineural hearing loss could be related to systemic lupus erythematosus, rheumatoid arthritis, Wegener's granulomatosis, ulcerative colitis, Sjögren's syndrome, amyloidosis, sarcoidosis or Cogan syndrome. However, the incidence of inner ear involvement in autoimmune diseases varies greatly 45,53 .…”

Section: Differential Diagnosismentioning

confidence: 99%

Síndrome de Vogt-Koyanagi-Harada e o seu acometimento multissistêmico

Mota¹,

Santos²

2010

Rev. Assoc. Med. Bras.

View full text Add to dashboard Cite

Vogt-Koyanagi-Harada's syndrome is a rare disease that affects tissues containing melanocytes, such as the eyes, central nervous system, inner ear and skin. Some ethnic groups have a higher probability of developing the disease, including Asians, Indians and Latin Americans and females are affected more often. Methods: Literature was reviewed in books, articles published on the internet and papers available in the online databases MEDLINE, LILACS and SciELO. Texts were selected that focused on otorhinolaryngological symptoms. Literature review: The disease probably has autoimmune etiology, with aggression occurring on the surface of melanocytes by promoting inflammatory reaction in which T lymphocytes predominate. The allele most often found in association with this disease is HLA DRB1*0405. Clinical manifestations are divided into four stages: prodromal, uveitic, chronic and recurrent. Otorhinolaryngological symptoms occur during the uveitic stage and are characterized by bilateral sensorineural hearing loss, tinnitus and vestibular symptoms. Diagnosis is made according to the diagnostic criteria for the disease. Treatment is primarily with corticosteroids. Conclusions: It is important that professionals in other specialties are able to recognize Vogt-Koyanagi-Harada's syndrome, because late diagnosis can lead to ocular and cutaneous sequelae.

show abstract

Section: Differential Diagnosismentioning

confidence: 99%