2006
DOI: 10.1590/s0004-27302006000500016
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Abstract: Rationale: Since ovarian function is only temporarily compromised by radioiodine therapy, many women with thyroid cancer treated with radioiodine can become pregnant. The present study evaluated the evolution of these pregnancies and the consequences for the offspring. Patients and methods: We retrospectively analyzed 78 pregnancies of 66 women submitted to total thyroidectomy, followed by radioiodine therapy (3.7-5.5 GBq 131 I, mean 4.64 GBq). In all patients, conception occurred one year after ablative thera… Show more

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Cited by 10 publications
(9 citation statements)
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“…Indeed, adverse perinatal outcomes were demonstrated in the postthyroidectomy group as compared to hypothyroidism due to other causes group and as compared to normal pregnancies. This stands in contrast to previous studies [2][3][4][5][6]9], in which complete thyroidectomy was not found to influence perinatal outcomes, and bare significant clinical importance as to counseling and management of such pregnancies.…”
Section: Discussioncontrasting
confidence: 96%
See 2 more Smart Citations
“…Indeed, adverse perinatal outcomes were demonstrated in the postthyroidectomy group as compared to hypothyroidism due to other causes group and as compared to normal pregnancies. This stands in contrast to previous studies [2][3][4][5][6]9], in which complete thyroidectomy was not found to influence perinatal outcomes, and bare significant clinical importance as to counseling and management of such pregnancies.…”
Section: Discussioncontrasting
confidence: 96%
“…Previous studies [8] have found adverse perinatal outcomes for hypothyroidism pregnancies; nevertheless, these studies did not investigate perinatal outcomes for patients following complete thyroidectomy. Previous studies about post-thyroidectomy pregnancies deal mostly with the effects of radioiodine treatment on perinatal outcomes [2][3][4][5][6]9], but not about the effects of hypothyroidism itself due to complete thyroidectomy.…”
Section: Discussionmentioning
confidence: 99%
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“…Specifically, only four (5.1%) of the 78 pregnancies resulted in spontaneous abortions, three (4%) of the 74 deliveries were preterm, and there was no case of stillbirth. The birth weight was >2,500 g in 94.6% of the children, and only one infant (1.3%) presented with a congenital malformation at birth (intraventricular communication) (44). A similar retrospective study in 76 women treated for DTC from 1971 to 2005 reported 49 pregnancies after I-131 therapy.…”
Section: I-131 and Pregnancy Outcomementioning
confidence: 89%
“…Previous studies in female patients have shown no significant effects of iodine-131 in treating thyroid cancers on fertility rate, birth weight, or congenital anomalies in offspring (22)(23)(24)(25)(26)(27)(28)(29). In our study, we have the same experience in treating patients for GD.…”
Section: Discussionmentioning
confidence: 70%