Contribuição da glicemia pós-desjejum para o controle glicêmico do paciente com diabetes melito tipo 2

Sartori, Maria Salete; Aragon, Flávio Ferrari; Padovani, Carlos Roberto; Pimenta, Walkyria de Paula

doi:10.1590/s0004-27302006000100008

Cited by 6 publications

(9 citation statements)

References 33 publications

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“…However, the diagnostic method for glucose levels used in these previous studies was a fasting glucose test, which is a better test for the diagnosis of diabetes. However, the measurement of capillary blood glucose is cited as an appropriate method for assessing the progression of diabetes and thereby constitutes a valid method that is easier to perform with truck drivers than fasting blood glucose tests [13, 24–26]. Furthermore, postprandial capillary blood glucose measurement is a method that adequately reflects glycated hemoglobin measurements [13, 24].…”

Section: Discussionmentioning

confidence: 99%

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Prevalence of cardiovascular risk factors among truck drivers in the South of Brazil

et al. 2014

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BackgroundTruck drivers work under conditions that predispose them to a high prevalence of risk factors for the development of cardiovascular disease (CVD); however, these factors have not been fully evaluated and are not usually considered to be within the scope of health or labor services.MethodsAn observational cross-sectional study was conducted on 250 long-distance truck drivers; the drivers were all male and were aged 18-60 years. The clinical evaluation consisted of an assessment of social habits and demographic data and an evaluation of risk factors for CVD at 3 time points separated by a one-week interval. To assess the associations with risk factors were used univariate and multivariate analysis. The suitability of the final model fit was assessed via the Hosmer-Lemeshow test. The significance level was set at 5%.ResultsAmong all of the subjects, the prevalence of physical inactivity was 72.8%; consumption of alcoholic beverages, 66.8%; routine use of some type of stimulant during work activities, 19.2%; and smoking, 29%. Only 20.8% had a healthy weight, and 58.2% had an abdominal circumference greater than 102 cm. A diagnosis of arterial hypertension was confirmed in 45.2%, and abnormal glucose levels were detected in 16.4%. Although some of the truck drivers were aware of these conditions, most were not taking specific medications. The logistic regression analysis shows that the odds of hypertension and abnormal glucose levels were increased in truck drivers with abdominal obesity. Age and the family history of premature CVD also increased the chances of hypertension and the abnormal blood glucose levels were related to II or III grade obesity.ConclusionLong-distance truck drivers showed a high prevalence of a cluster of cardiovascular risk factors; these risk factors make the drivers highly susceptible to the development of CVD. The associated risk factors, low compliance with drug treatment, and unique features of this profession suggest that traditional precautions are not sufficient to change this scenario.

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Section: Discussionmentioning

confidence: 99%

“…Before starting the examination, the researchers ensured that the participants had not eaten for at least two hours. Truck drivers were classified as having abnormal glucose levels if their values were greater than 140 mg/dl [13] or if they used hypoglycemic drugs, regardless of the results of the capillary glucose test.…”

Section: Methodsmentioning

confidence: 99%

Prevalence of cardiovascular risk factors among truck drivers in the South of Brazil

et al. 2014

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“…Measurement of glycated hemoglobin is the gold-standard test in the assessment of glycemic control in patients with diabetes mellitus and is a useful test in the follow-up of diabetic patients, as well as in the assessment of the status of blood glucose over the previous 3 months (6,7) . The correlation of glycated hemoglobin values with fasting blood sugar values is still not well defined (8,9) . Values of fasting blood sugar have a better association with glycated hemogloAerobic bacterial microbiota of the conjunctiva in diabetic patients with normal and altered glycated hemoglobin levels in two regions in Brazil Microbiota bacteriana aeróbica conjuntival em pacientes diabéticos com hemoglobina glicada normal e alterada em duas regiões brasileiras bin values when they are higher, i.e., in situations of poor glycemic control (7,8) .…”

Section: Introductionmentioning

confidence: 99%

“…The correlation of glycated hemoglobin values with fasting blood sugar values is still not well defined (8,9) . Values of fasting blood sugar have a better association with glycated hemogloAerobic bacterial microbiota of the conjunctiva in diabetic patients with normal and altered glycated hemoglobin levels in two regions in Brazil Microbiota bacteriana aeróbica conjuntival em pacientes diabéticos com hemoglobina glicada normal e alterada em duas regiões brasileiras bin values when they are higher, i.e., in situations of poor glycemic control (7,8) . Studies show that the bacterial flora of healthy individuals is formed by Staphylococcus epidermidis (4,10,11) , S. aureus, Corynebacterium sp, and Propineobacterium acne (13) .…”

Section: Introductionmentioning

confidence: 99%

Aerobic bacterial microbiota of the conjunctiva in diabetic patients with normal and altered glycated hemoglobin levels in two regions in Brazil

Moreno¹,

Moreno²,

Sousa³

2014

Arquivos Brasileiros De Oftalmologia

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Purpose: To study the aerobic bacterial microbiota of the conjunctiva in diabetic patients with regard to the management of diabetes, assessed using glycated hemoglobin levels. Methods: A cross-sectional study was conducted using conjunctival smears of diabetic patients from both sexes and with different ages, residing in two different Brazilian cities (Sorocaba and Rio Branco). A control group of non-diabetic patients was also included. The diabetic patients were considered to have controlled diabetes when their glycated hemoglobin level was ≤7% and blood glucose level was ≤126 mg/dL. Patients with non-controlled diabetes were those with glycated hemoglobin levels >7% and blood glucose levels >126 mg/dL. The samples obtained were inoculated in Brain-Heart Infusion broth and in culture media for aerobic bacteria (blood and chocolate agars); bacterial growth was evaluated in a microbiology laboratory. Results: A total of 120 eyes of 120 patients were included in the present study. The percentage of cultures in which bacterial growth was observed was greater in diabetic patients, although the difference was not statistically significant (p=0.103). There was a greater trend toward bacterial growth in the conjunctiva of diabetic patients with altered fasting blood glucose. There was no difference in the frequency of bacterial growth on the conjunctiva between diabetic patients with normal or altered glycated hemoglobin levels. In Sorocaba, conjunctival bacterial growth was similar to that observed in Rio Branco. The microorganism most frequently detected in the present study was Staphylococcus epidermidis, followed by Staphylococcus aureus, Proteus mirabilis, and Escherichia coli. Conclusions: There was no difference between diabetic patients with normal or altered glycated hemoglobin levels. The microorganisms found were similar to those found in studies investigating the conjunctival bacterial flora of diabetic and non-diabetic patients.

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“…Tal resultado seria explicado pela variação circadiana da produção hepática de glicose que ocorre em DM2, caracterizada pelo pico próximo ao amanhecer e declínio progressivo ao longo do dia (23). Em estudo nacional recente (24), realizado com glicemias plasmáticas, ficou evidenciado que este era o momento de maior excursão glicêmica, além de apresentar maior correlação com a HbA1c. Em nosso estudo, no entanto, não encontramos essa correlação.…”

Section: Discussionunclassified

Hiperglicemia pós-prandial em pacientes com diabetes melito tipo 2

Cruzes

Bosco

Pandini

et al. 2008

Arq Bras Endocrinol Metab

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RESUMOObjetivos: Por meio da análise de um grupo de pacientes com DM2, temos por objetivos: avaliar por monitoração da glicose subcutânea (MGSG) as excursões pós-prandiais da glicose subcutânea; analisar as correlações da glicose subcutânea e glicemias capilares com a HbA1c e avaliar a eficácia, a segurança e a tolerabilidade da MGSC. Métodos: Foram analisados 40 pacientes com DM2, com HbA1c até 7,3%, em uso de agentes orais e com menos de 10 anos de diagnóstico. Foram submetidos à MGSC por 72 horas, cujos dados foram confrontados com a HbA1c e as glicemias capilares. Resultados: A excursão média da glicose subcutânea do desjejum foi estatisticamente maior que a do jantar (95%IC -24,96 a -1,66). A razão excursão da glicose subcutânea/conteúdo de carboidrato da refeição foi estatisticamente maior no desjejum que nas demais refeições (p = 0,001). Não houve correlação entre as taxas de glicose subcutânea e as glicemias capilares com HbA1c. Não houve complicações com o uso da MGSC. Conclusões: As excursões de glicose subcutânea predominaram no desjejum. Não se encontrou correlação entre HbA1c e parâmetros de controle glicêmico. A MGSC mostrou-se eficaz, segura e bem tolerada nesse grupo de pacientes. ABSTRACT Post-Prandial Hyperglycemia in Type 2 Diabetes Patients.Objectives: Through the analysis of a group of type 2 diabetes patients, the aims of this study are: to evaluate through CGMS (continuous glucose monitoring system) the post-prandial subcutaneous glucose excursions; to analyze the correlations between subcutaneous glucose and capillary glycemia with HbA1c and to evaluate the effectiveness, safety and broadmindedness of the CGMS. Methods: Forty type 2 diabetes patients were analyzed, with HbA1c until 7.3%, in use of oral agents and within less than a ten-year diagnosis. They were submitted to CGMS for 72h, whose data were compared with HbA1c and capillary glycemia. Results: The average subcutaneous glucose excursion at breakfast was statistically bigger than at dinner (95%CI -24,96 a -1,66). The subcutaneous glucose excursion/meal carbohydrates content ratio was statistically bigger at breakfast than at other meals (p 0,001). There was no correlation between the levels of subcutaneous glucose and capillary glycemia with HbA1c. There weren't complications using CGMS. Conclusions: The subcutaneous glucose excursions were predominant at breakfast. There were no correlations between HbA1c and glycemic control parameters. CGMS showed itself efficient, secure and well tolerated in this group of patients. (Arq Bras Endocrinol Metab 2008; 52/4:642-648)

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Contribuição da glicemia pós-desjejum para o controle glicêmico do paciente com diabetes melito tipo 2

Abstract: Measurement of post-breakfast PG showed to be another valuable tool for type 2 diabetic glucose control monitoring.

Cited by 6 publications

References 33 publications

Prevalence of cardiovascular risk factors among truck drivers in the South of Brazil

Prevalence of cardiovascular risk factors among truck drivers in the South of Brazil

Aerobic bacterial microbiota of the conjunctiva in diabetic patients with normal and altered glycated hemoglobin levels in two regions in Brazil

Hiperglicemia pós-prandial em pacientes com diabetes melito tipo 2

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