2009
DOI: 10.1590/s0001-37652009000200007
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Larvicidal activity of the water extract of Moringa oleifera seeds against Aedes aegypti and its toxicity upon laboratory animals

Abstract: In this work, biological effects of the water extract of Moringa oleifera seeds (WEMOS) were assessed on eggs and 3 rd instar larvae of Aedes aegypti and on its toxicity upon laboratory animals (Daphnia magna, mice and rats). Crude WEMOS showed a LC 50 value of 1260μg/mL, causing 99.2 ± 2.9% larvae mortality within 24 h at 5200μg/mL, though this larvicidal activity has been lost completely at 80 • C/10 min. WEMOS did not demonstrate capacity to prevent egg hatching. After extensive dialyses of the crude WEMOS … Show more

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Cited by 52 publications
(47 citation statements)
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“…In fact, cytochemistry analysis performed in [33] detected a large amount of cotyledonary protein bodies. The oil content (363.2 ± 2.6 g / kg) is greater than that of soybean varieties [32]. The main saturated fatty acids found in this oil are behenic, palmitic, stearic and arachidic, also containing appreciable quantities of unsaturated fatty acids, especially oleic (65-80%) [28,31], which are desirable in terms of applications and nutritional stability for cooking and frying.…”
Section: Taxonomy Distribution and General Use And Consumptionmentioning
confidence: 93%
See 1 more Smart Citation
“…In fact, cytochemistry analysis performed in [33] detected a large amount of cotyledonary protein bodies. The oil content (363.2 ± 2.6 g / kg) is greater than that of soybean varieties [32]. The main saturated fatty acids found in this oil are behenic, palmitic, stearic and arachidic, also containing appreciable quantities of unsaturated fatty acids, especially oleic (65-80%) [28,31], which are desirable in terms of applications and nutritional stability for cooking and frying.…”
Section: Taxonomy Distribution and General Use And Consumptionmentioning
confidence: 93%
“…The approximate composition of M. oleifera seeds shows levels of proteins (377.5 ± 1.9 g/kg dry matter) higher than those found in important legumes for human nutrition (149-220 g/kg) [30][31][32]. In fact, cytochemistry analysis performed in [33] detected a large amount of cotyledonary protein bodies.…”
Section: Taxonomy Distribution and General Use And Consumptionmentioning
confidence: 99%
“…Entre 1981 e 2010, das 1.073 novas entidades químicas (New Chemical Entities -NCEs) aprovadas como medicamento pelo Food and Drug Administration (FDA) dos Estados Unidos, apenas 36% foram classificadas como verdadeiramente sintéticas, sendo que 64% são moléculas naturais, derivadas ou sintetizadas com base em compostos naturais. Apesar do interesse na modelagem molecular, na química combinatória e outras técnicas de síntese química, os produtos naturais e, particularmente, as plantas, permanecem, portanto, como uma importante fonte de novos agentes terapêuticos contra infecções (fúngicas ou bacterianas), radicais livres, mosquitos vetores de doenças, câncer, dislipidemias e imunomodulação (Butler, 2004;Balunas & Kingnorn, 2005;Ferreira et al, 2009Ferreira et al, , 2011Newman & Cragg, 2012;Carvalho et al, 2013;Farias et al, 2013;Santos et al, 2013).…”
Section: Introductionunclassified
“…Assim, uma alternativa está no processo de flotação por dissolvido (FAD), que quando comparada ao processo de sedimentação, se apresenta viável com relação a remoção de células intactas de cianobactérias, além de diminuir o tempo de contato do coagulante com a parede celular, evitando assim o seu rompimento e consequentemente maior liberação de toxinas intracelulares para o meio. (Oliveira, 2005) E como auxiliar ao processo de C/F a Moringa aparece como uma possibilidade interessante para a floculação de microalgas, visto que já demonstrou o seu poder floculante até com microorganismos, é um material barato e apresenta baixa toxicidade (Ferreira et al 2009). …”
Section: Introductionunclassified