Uptake of iron from different compounds by enteroinvasive Escherichia coli

́Agnol, Monique Dall; Martinez, Marina Baquerizo

doi:10.1590/s0001-37141999000200012

Cited by 4 publications

(5 citation statements)

References 21 publications

(14 reference statements)

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“…Contrary to what it found for the ability of EIEC to use iron compounds (8), the pattern of expression of IROMPs is serotype-specific. We investigated the regulation of expression of the major IROMP by growing the cells in iron-replete medium and ironlimited medium, separating their outer membranes and subjecting them to SDS-PAGE.…”

Section: Discussioncontrasting

confidence: 96%

“…HLf is probably a relevant source of iron for EIEC, due to its presence in gastrointestinal mucosal surfaces. In a study performed in our laboratory, several EIEC strains were able to use HLf (8). We investigated the binding of HLf to outer membrane receptors and two bands (39 and 43 kDa) showed binding specificity to HLf, and neither was iron-regulated.…”

Section: Discussionmentioning

confidence: 99%

“…Those strains were checked for their ability to use iron from different host sources, such as heme compounds and the glycoproteins transferrin and lactoferrin. All sources were used by EIEC strains (8). In the present article, the EIEC IROMPs were studied.…”

Section: Agda Andradementioning

confidence: 99%

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The iron uptake mechanisms of enteroinvasive Escherichia coli

Andrade¹,

́Agnol²,

Newton³

et al. 2000

Braz. J. Microbiol.

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Enteroinvasive Escherichia coli strains (EIEC) of different serotypes isolated from patients with acute diarrhea were examined for the ability to produce siderophores and iron-regulated outer membrane proteins (IROMP). For iron starvation cultures were grown at 37°C in LB supplied with 200 µM of α-α'dypirydil. All strains produced enterobactin and twelve (40%) produced aerobactin. The strains showed IROMP varying from 67-82 kDa. Proteins were either induced or stimulated by the iron starvation. Differences were observed in the electrophoretic profile among the serotypes, originating 5 electrophoretic profiles. All serotypes expressed proteins of 82 kDa (FepA)

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Section: Discussioncontrasting

confidence: 96%

Section: Discussionmentioning

confidence: 99%

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The iron uptake mechanisms of enteroinvasive Escherichia coli

Andrade¹,

́Agnol²,

Newton³

et al. 2000

Braz. J. Microbiol.

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“…Overall, the proportions of isolates that were capable of using haemoglobin and haemoglobin-haptoglobin were 80 and 63 %, respectively. Utilization of haemoglobin, transferrin and lactoferrin has also been reported previously (Law et al, 1992;Dall'Agnol & Martinez, 1999). E. coli was considered to be incapable of using the haemoglobin-haptoglobin complex (Eaton et al, 1982, Helms et al, 1984; however, the uropathogenic strain CFT073, which possesses multiple iron-uptake systems, can use this complex (Torres et al, 2001).…”

Section: Iron Utilization Studiesmentioning

confidence: 82%

The Yersinia high-pathogenicity island and iron-uptake systems in clinical isolates of Escherichia coli

Koczura

Kaznowski

2003

Journal of Medical Microbiology

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The ability to acquire iron is crucial for bacteria during an infection. The capacity of 35 strains of Escherichia coli, isolated from clinical specimens, to use various strategies to obtain iron was analysed. The isolates employed several iron-uptake mechanisms, including production of enterobactin (86 %) and aerobactin (71 %). The majority of the isolates also excreted yersiniabactin, which is encoded by the Yersinia high-pathogenicity island (HPI). However, PCR analysis of the Yersinia HPI revealed diversity in its genetic organization. Use of human transferrin (91 %), lactoferrin (94 %), haemoglobin (80 %) and haemoglobin-haptoglobin complex (63 %) as the sole source of iron was common among E. coli isolates. Multiple iron-uptake systems may be of benefit to bacteria during an infection.

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“…It was shown that EIEC has a high adaptability, using, if necessary, the iron capture system that consumes less energy. The ability to capture Fe from different sources can facilitate the development of infectious processes by this bacterium 412, 413…”

Section: Enteroinvasive E Colimentioning

confidence: 99%

Diarrheagenic Escherichia coli

Gomes

Elias

Scaletsky

et al. 2016

Brazilian Journal of Microbiology

366

315

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Most Escherichia coli strains live harmlessly in the intestines and rarely cause disease in healthy individuals. Nonetheless, a number of pathogenic strains can cause diarrhea or extraintestinal diseases both in healthy and immunocompromised individuals. Diarrheal illnesses are a severe public health problem and a major cause of morbidity and mortality in infants and young children, especially in developing countries. E. coli strains that cause diarrhea have evolved by acquiring, through horizontal gene transfer, a particular set of characteristics that have successfully persisted in the host. According to the group of virulence determinants acquired, specific combinations were formed determining the currently known E. coli pathotypes, which are collectively known as diarrheagenic E. coli. In this review, we have gathered information on current definitions, serotypes, lineages, virulence mechanisms, epidemiology, and diagnosis of the major diarrheagenic E. coli pathotypes.

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Uptake of iron from different compounds by enteroinvasive Escherichia coli

Cited by 4 publications

References 21 publications

The iron uptake mechanisms of enteroinvasive Escherichia coli

The iron uptake mechanisms of enteroinvasive Escherichia coli

The Yersinia high-pathogenicity island and iron-uptake systems in clinical isolates of Escherichia coli

Diarrheagenic Escherichia coli

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