2022
DOI: 10.1590/2317-6431-2021-2599
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Abstract: RESUMO Objetivos Revisar sistematicamente a literatura sobre o impacto do tratamento medicamentoso nas funções de voz, fala e deglutição de indivíduos adultos com esclerose lateral amiotrófica esporádica, mensuradas por meio de escalas e seus respectivos escores, em relação ao grupo placebo. Estratégia de pesquisa A busca foi realizada com base na estratégia PICO (problema/população/paciente; intervenção; comparação/controle; desfecho/outcome). As palavras-chave foram selecionadas a partir de consulta aos De… Show more

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Cited by 1 publication
(2 citation statements)
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“…Despite these sequelae, treatment targeting bulbar dysfunction in ALS are lacking with routine use of the current palliative standard of care management approaches. This includes compensatory approaches such as dietary and environmental modifications, feeding tube placement, and alternative and assistive communication interventions that are implemented reactively once dysarthria or dysphagia manifest and are clinically detected 7,8 . The lack of targeted treatment options to proactively improve or maintain bulbar function represents a crucial clinical management gap in the care of pALS 9–11 .…”
Section: Introductionmentioning
confidence: 99%
See 1 more Smart Citation
“…Despite these sequelae, treatment targeting bulbar dysfunction in ALS are lacking with routine use of the current palliative standard of care management approaches. This includes compensatory approaches such as dietary and environmental modifications, feeding tube placement, and alternative and assistive communication interventions that are implemented reactively once dysarthria or dysphagia manifest and are clinically detected 7,8 . The lack of targeted treatment options to proactively improve or maintain bulbar function represents a crucial clinical management gap in the care of pALS 9–11 .…”
Section: Introductionmentioning
confidence: 99%
“…The lack of targeted treatment options to proactively improve or maintain bulbar function represents a crucial clinical management gap in the care of pALS 9–11 . To date, no efficacious treatments have been identified to prolong safe and efficient oral intake or functional communication in pALS 7 …”
Section: Introductionmentioning
confidence: 99%