“…Due to the heterogeneity of studies, a meta-analysis was not appropriate, and the results were described qualitatively. Based on the OCEBM 2011 Levels of Evidence table 29 the majority of studies (N.=17; 77.3%) were level 4 (six case report, 7,11,17,19,22,28 eight case series, 9,10,13,14,16,21,24,27 three historical cohort 20,23,26 ), whereas the remaining five were level 3 (four cohort studies 8,12,15,25 and one cross-sectional 18 study). No RCT or QRCTs were found in this update (Table I).…”