Plants of the Araceae family for malaria and related diseases: a review

Frausin, Gina; Lima, Renata Braga Souza; Hidalgo, A. F.; Ming, Lin Chau; Pohlit, Adrian Martin

doi:10.1590/1983-084x/14_024

Cited by 13 publications

(11 citation statements)

References 33 publications

(19 reference statements)

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“…Lengths of the poles are used to line the bottoms of dugout canoes (Duke , Méndez ). In some parts of South America, it has been documented that this species is used as antidote, antimalarial, antidiuretic or animal feed, as well as, to treat various health conditions, such as nosebleeds, abscesses, tumors, respiratory conditions, rheumatism and ulcers (Plowman , Amorozo and Gély , Amarante et al , dos Santos et al , Frausin et al ).…”

Section: Resultsmentioning

confidence: 99%

The emergent macrophyte Montrichardia linifera (Arruda) Schott (Alismatales: Araceae), a rekindled old friend from the Pacific Slope of lower Central America and western Colombia

Ortíz

Ibáñez²,

Trujillo‐Trujillo

et al. 2020

Nordic Journal of Botany

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The genus Montrichardia are among the most remarkable emergent macrophytes in tropical wetlands. It occurs exclusively in the Neotropics and contains two living species, M. linifera (Arruda) Schott and M. arborescens (L.) Schott. Montrichardia linifera has been reported mainly in the Amazon basin (southern Venezuela to Guyana, Brazil, Ecuador and Peru), whereas M. arborescens occurs in Central America (Mexico to Panama), the Lesser Antilles and northern South America. Based on our review of herbarium specimens from Central America and Colombia, as well as field documentation in Panama, we hereby provide the first report of the occurrence of M. linifera in Panama, Central America and western Colombia. Furthermore, this finding represents the first record on the Pacific Slope for this species in the Neotropics. The habitat, ecology, life-form, taxonomic remarks and morphological characteristics of the species are presented, discussed and illustrated. Additionally, a key for the species of the genus Montrichardia is included; we also provide a discussion about the helophyte concept for the genus Montrichardia.

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Section: Resultsmentioning

confidence: 99%

The emergent macrophyte Montrichardia linifera (Arruda) Schott (Alismatales: Araceae), a rekindled old friend from the Pacific Slope of lower Central America and western Colombia

Ortíz

Ibáñez²,

Trujillo‐Trujillo

et al. 2020

Nordic Journal of Botany

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“…Most of these species are indigenous to Pakistan, Malaysia, Indonesia, tropical Africa and America (Frausin et al. 2015). It has been reported that S .…”

Section: Introductionmentioning

confidence: 99%

“…Moreover, some pharmacological activities of the Araceae family reported include antimicrobial, antimalarial, antispasmodic, anticancer, vasomodulator and bronchodilator (Frausin et al. 2015).…”

Section: Introductionmentioning

confidence: 99%

Sauromatum guttatum extract promotes wound healing and tissue regeneration in a burn mouse model via up-regulation of growth factors

Said

Wahid

Bashir

et al. 2019

Pharmaceutical Biology

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Contexts: Sauromatum guttatum (Wall.) Schott (Araceae) has been traditionally used for the treatment of wounds.Objectives: This study evaluates the healing and tissue regeneration potential of S. guttatum extract in burn wounds.Materials and methods: S. guttatum extract was analysed using various chemical tests, thin layer chromatography (TLC) and high-performance liquid chromatography (HPLC). Moreover, the extract was tested against burn associated bacteria and minimum inhibitory concentration (MIC) was also calculated. Wound healing and tissue regeneration potential was assessed using a thermally induced burn BALBc mouse model. S. guttatum extract (2% w/w) prepared in petroleum jelly, vehicle and positive control [silver sulfadiazine (SD)] groups was applied three times a day. The treatment was continued for 15 d and wound closure was measured and photographed on day 5, 10 and 15. The burnt tissues excised from wounds were subjected to histological and comparative gene expression analysis.Results: The results of the chemical tests indicated the presence of alkaloids, saponins, phenols, phytosterols, tannins, and flavonoids, while TLC and HPLC analysis indicated the presence of various compounds. The extract showed excellent activity against the tested pathogens. The lowest MIC (125 µg/mL) was observed against Staphylococcus aureus. A considerable decrease in wound area (72%) was observed in extract-treated group. Histological examination of extract-treated group showed good signs of wound healing with complete re-epithelialization and better tissue regeneration. Comparative gene expression analysis revealed the up-regulation of wound healing related PDGF, EGF and FGF genes.Conclusions: S. guttatum extract may be used to isolate bioactive constituents for the treatment of burn wounds.

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“…Several extracts of plant origin have been tested for their antimalarial activity with remarkably encouraging results [2,3,4,5,6,7,8,9,10,11]. In this study, attention was focussed mainly on Erythrina abyssinica; a branched, deciduous shrub or tree belonging to the genus Erythrina with rounded, spreading crown growing up to 15 metres tall.…”

Section: Introductionmentioning

confidence: 99%

In vivo Evaluation of Anti-malarial Activity of Stem and Root Extracts of Erythrina abyssinica

Onyango

Midiwo

2019

EJMP

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Aims: The aim of the study was to determine the in vivo anti-malarial activity of stem and root extracts of E. abyssinica using the 4-day suppressive in vivo anti-malarial test. Methodology: Female mice weighing approximately 20±2 g were intra-peritoneally injected with mice passaged Plasmodium berghei parasites. The extracts were then administered orally 2 h post-infection and, subsequently, daily for 4 days. On the 4th day, blood smears were prepared from all the mice, stained with giemsa and parasitaemia as well as chemosuppression determined. Results: Comparatively, the root extracts exhibited higher chemosuppression than stem extracts and the level of chemosuppression was dose dependent being the highest at 50 mg/kg and lowest at 12.5 mg/kg. Survival time in extract treated and chloroquine treated groups was 2 to 3 fold higher than the –ve control. Conclusion: These findings suggest that the root extracts are more efficacious in suppressing the development of full blown malaria compared to stem extracts and may be a useful candidate in managing malaria in future.

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Plants of the Araceae family for malaria and related diseases: a review

Cited by 13 publications

References 33 publications

The emergent macrophyte Montrichardia linifera (Arruda) Schott (Alismatales: Araceae), a rekindled old friend from the Pacific Slope of lower Central America and western Colombia

The emergent macrophyte Montrichardia linifera (Arruda) Schott (Alismatales: Araceae), a rekindled old friend from the Pacific Slope of lower Central America and western Colombia

Sauromatum guttatum extract promotes wound healing and tissue regeneration in a burn mouse model via up-regulation of growth factors

In vivo Evaluation of Anti-malarial Activity of Stem and Root Extracts of Erythrina abyssinica

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