Declínio cognitivo subjetivo, comprometimento cognitivo leve e demência - diagnóstico sindrômico: recomendações do Departamento Científico de Neurologia Cognitiva e do Envelhecimento da Academia Brasileira de Neurologia

Smid, Jerusa; Neto, Adalberto Studart; César-Freitas, Karolina Gouveia; Dourado, Marcia Cristina Nascimento; Kochhann, Renata; Barbosa, Breno José Alencar Pires; Schilling, Lucas Porcello; Balthazar, Márcio Luiz Figueredo; Frota, Norberto Anízio Ferreira; Souza, Leonardo Cruz de; Caramelli, Paulo; Bertolucci, Paulo Henrique Ferreira; Chaves, Márcia Lorena Fagundes; Brucki, Sônia Maria Dozzi; Nitrini, Ricardo; Resende, Elisa de Paula França; Vale, Francisco Assis Carvalho

doi:10.1590/1980-5764-dn-2022-s101pt

Cited by 5 publications

(1 citation statement)

References 95 publications

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“…Diseases that affect the functions of human higher nervous activity and are accompanied by severe cognitive impairment account for a significant proportion of diseases recorded in human populations. The number of cases of such diseases has been rapidly increasing in recent years, due to socio-economic cataclysms and the general aging of the population [1,2]. Neuropathology is generally considered as one of the main health problems, which determines the high social significance and relevance of research aimed at elucidating the causes of such diseases, as well as developing systems for preventing and correcting disorders of human brain activity.…”

Section: Introductionmentioning

confidence: 99%

Are Ischemic Stroke and Alzheimer’s Disease Genetically Consecutive Pathologies?

Filippenkov,

Khrunin,

Mozgovoy

et al. 2023

Biomedicines

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Complex diseases that affect the functioning of the central nervous system pose a major problem for modern society. Among these, ischemic stroke (IS) holds a special place as one of the most common causes of disability and mortality worldwide. Furthermore, Alzheimer’s disease (AD) ranks first among neurodegenerative diseases, drastically reducing brain activity and overall life quality and duration. Recent studies have shown that AD and IS share several common risk and pathogenic factors, such as an overlapping genomic architecture and molecular signature. In this review, we will summarize the genomics and RNA biology studies of IS and AD, discussing the interconnected nature of these pathologies. Additionally, we highlight specific genomic points and RNA molecules that can serve as potential tools in predicting the risks of diseases and developing effective therapies in the future.

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Section: Introductionmentioning

confidence: 99%

Are Ischemic Stroke and Alzheimer’s Disease Genetically Consecutive Pathologies?

Filippenkov,

Khrunin,

Mozgovoy

et al. 2023

Biomedicines

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Assessment of cognitive function in elderly patients with heart failure

Silva,

Sampaio,

Guimarães

et al. 2024

Rev. Assoc. Med. Bras.

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Effects of seated Senior Dance® on cognitive functions in older adults with and without cognitive decline: a controlled clinical trial

Piazentin,

Chagas,

Payão

2024

Rev. bras. geriatr. gerontol.

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Objective To analyze the effects of Senior Dance® (SD) on cognitive aspects in older adults aged 60 to 85 years. Method Non-randomized controlled clinical trial consisting of two groups: (G1) institutionalized older adults with cognitive decline and (G2) non-institutionalized older adults without cognitive decline. Assessments were conducted using the Mini-Mental State Examination (MMSE), Brief Cognitive Screening Battery (BCSB), and Clinical Dementia Rating (CDR). The SD sessions were conducted in a seated format, for 12 weeks, twice a week, with a duration of 60 minutes each. The Mann-Whitney and Wilcoxon non-parametric tests were used for pre-intervention and post-intervention comparisons. Results G1 consisted of 15 older adults with mild cognitive impairment (MCI) and mild dementia, while G2 consisted of 32 older adults. The Wilcoxon test showed a statistically significant difference (p value ≤0.050) in various cognitive domains assessed by the MMSE and BCSB in both groups. Specifically, significant improvements were observed in the domains of attention, calculation, and language in G1, as well as in language in G2, according to the MMSE. Additionally, significant changes were noted in the domains of incidental memory, recognition, and verbal fluency in G1, and in incidental memory, immediate memory, delayed memory, recognition, and clock drawing in G2, as assessed by the BCSB. Conclusion It is concluded that SD had positive impacts on the cognitive functions of participants in both groups, contributing to prevention and health promotion.

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Declínio cognitivo subjetivo, comprometimento cognitivo leve e demência - diagnóstico sindrômico: recomendações do Departamento Científico de Neurologia Cognitiva e do Envelhecimento da Academia Brasileira de Neurologia

Cited by 5 publications

References 95 publications

Are Ischemic Stroke and Alzheimer’s Disease Genetically Consecutive Pathologies?

Are Ischemic Stroke and Alzheimer’s Disease Genetically Consecutive Pathologies?

Assessment of cognitive function in elderly patients with heart failure

Effects of seated Senior Dance® on cognitive functions in older adults with and without cognitive decline: a controlled clinical trial

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