Intervalos de referência sanguíneos e a influência da idade e sexo sobre parâmetros hematológicos e bioquímicos de ovinos da raça Santa Inês criados na Amazônia Oriental

Abstract

RESUMOO hemograma e o perfil bioquímico são usados para diagnosticar doenças em animais domésticos. Esses exames podem ser influenciados pela idade, sexo, nutrição, raça, espécie e condições ambientais. Portanto, dados de uma região não podem ser totalmente extrapolados para animais criados em regiões geograficamente distintas. Isso se aplica a ovinos criados no Bioma Amazônico. O objetivo deste estudo foi determinar os valores hematológicos e bioquímicos de ovinos Santa Inês, de diferentes idades e gêneros criados na Amazônia oriental. Foram examinados 91 ovinos divididos em três grupos: G1 (3-6 meses de idade, n = 31); G2 (7 a 24 meses de idade, n = 30) e G3 (mais de 24 meses de idade, n = 30). O hemograma e as determinações bioquímicas foram realizados com um contador automático e um analisador semi-automático, respectivamente. Os resultados foram comparados pelo teste de Tukey. O número de eritrócitos, índices eritrocitários, plaquetograma, número de eosinófilos, teor de proteína total, de ureia e de creatinina foram influenciados pela idade dos animais. O coeficiente de variação dos eritrócitos e a concentração de creatinina foram influenciados pelo sexo, sendo maiores nos machos. A relação neutrófilos:linfócitos (N:L) foi maior que um para todos os grupos etários. Neste estudo foram determinados valores de referência para ovinos criados na Amazônia Oriental. Além disso, demonstrou-se que ao interpretar exames hematológicos e bioquímicos de ovinos, a idade e o sexo devem ser considerados. PALAVRAS-CHAVE: Hemograma, Leucograma, Diagnóstico, Patologia Clínica Blood reference intervals and the influence of age and gender on hematologic and biochemical parameters of Santa Ines sheep bred in the eastern Amazon ABSTRACTBlood count and biochemical tests are used to diagnose diseases in domestic animals. These tests can be influenced by age, gender, nutrition, breed, species and environmental conditions. Thus, data from one region should not be extrapolated to animals raised in other regions. The objective of this study was to determine the hematological and biochemical values of different ages and genders of Santa Inês sheep, raised in the eastern Amazon. There were examined 91 sheep that were assigned to three groups: G1 (three to six months old, n = 31); G2 (seven to 24 months old, n = 30) and G3 (above 24 months old, n = 30). The blood cell count, white blood count and biochemical determinations were made with an automatic counter and a semi-automatic analyzer, respectively. Mean values were compared using the Tukey test. The number of erythrocytes, the red blood indices, the thrombogram, eosinophils, total protein, urea and creatinine concentrations were influenced by the age of the animals. The erythrocyte coefficient of variation and the creatinine concentration were influenced by gender, and were greater in males. The neutrophil:lymphocyte (N:L) ratio was greater than one for all age groups. This study led to the determination of reference values for sheep raised in the Eastern Amazon and demonstrated that ...

Effects of age and sex on blood biochemistry of dorper lambs

“…The sex of the animal did not influence the biochemical variables of the sheep in this study (p > 0.05), corroborating the findings of Souza et al (2016) and Eshratkhah et al (2010), and differing from those of other researchers TELEB et al, 2009;MADUREIRA et al, 2013;SITMO, 2014;CARLOS et al, 2015;LIMA et al, 2015). All animals in this study were prepubescent.…”

“…Regarding enzymes, the values of ALT remained within the intervals cited by Ramos et al (1994) and Sitmo (2014), and the values of AST were compatible with those cited in previous studies (RAMOS et al, 1994;KANEKO et al, 2008;LEPHERD et al, 2009;MEIRA JÚNIOR et al, 2009;MADUREIRA et al, 2013;SITMO, 2014;SOUZA et al, 2014;LIMA et al, 2015;STEVANOVIC et al, 2015). The values of GGT were also similar to those in previous studies (ROUBIES et al, 2006;KANEKO et al, 2008;LEPHERD et al, 2009;MEIRA JÚNIOR et al, 2009;STEVANOVIC et al, 2015); and the values of ALP were similar to those of Kaneko et al (2008), Lepherd et al (2009), Madureira et al (2013), and Sitmo (2014).…”

“…Protein and metabolite values of the sheep in the present study were compared with those available in the literature; the values of TP, ALB, and GLB remained within the intervals reported in previous studies (ROUBIES et al, 2006;LEPHERD et al, 2009;MEIRA JÚNIOR et al, 2009;MADUREIRA et al, 2013;SOUZA et al, 2014;CARLOS et al, 2015;STEVANOVIC et al, 2015). The GLU, TG, and t CHOL values remained within the intervals obtained by Carlos et al (2015); the HDL-C, LDL-C, and VLDL-C values were close to the values of Sitmo (2014), and the CRE and urea values were within the intervals cited by other researchers (MADUREIRA et al, 2013;SITMO, 2014;CARLOS et al, 2015;LIMA et al, 2015).…”

“…The observation of higher CRE concentrations (p < 0.05) in M1 and M2 contradicts Lima et al (2015), who observed an age-related creatinine increase in sheep due to the higher muscle mass. The higher CRE values in sheep aged up to 61 days in this study are attributed to the higher demand for phosphocreatine for muscle mass gain; creatinine is formed by the breakdown of phosphocreatine for the release of energy in skeletal muscle (CARLOS et al, 2015).…”

“…Several factors have been described as possible causes of significant changes in the blood biochemistry of sheep . The blood biochemical profile may be influenced by age, sex, nutrition, breed, species, and environmental conditions (LIMA et al, 2015), as animals with different physiological and behavioral characteristics have different nutritional, energy, and metabolic requirements, which are reflected in their biochemical profiles (MADUREIRA et al, 2013). This subject inspired several researchers to establish reference intervals for sheep of different breeds, regions, and management systems.…”