Atividade antimicrobiana de óleos essenciais da Amazônia

Lobato, Almira M.; Ribeiro, A. Ribeiro e; Pinheiro, Maria de Fátima da Silva; Maia, José Guilherme S.

doi:10.1590/1809-43921989191363

Cited by 10 publications

(3 citation statements)

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“…O maior halo de inibição (35 mm) foi obtido por ação do OE contra a cepa IV2, havendo inibição total do crescimento bacteriano induzida pela concentração de 100 mg.mL -1 . Esses resultados foram superiores aos apresentados por Lobato et al (1989) que, ao avaliarem o OE das folhas de A. zerumbet sobre S. aureus, obtiveram halos de inibição que variaram de 0,7 a 14 mm. Essa diferença de ação pode ser atribuída à origem diversa, que determina diferença na composição dos mesmos (Lapa et al, 1999).…”

Section: Resultsunclassified

Composição química e eficácia do óleo essencial e do extrato etanólico de Alpinia zerumbet sobre Staphylococcus aureus

Castro

Lima

Vasconcelos³

et al. 2016

Arq. Inst. Biol.

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ABSTRACT:The present work describes the antibacterial activity of the essential oil and the ethanol extract from leaves of Alpinia zerumbet (colônia) on Staphylococcus aureus strains isolated from cows with subclinical mastitis and standard strains ATCC 29213 and ATCC 25923, using the agar diffusion method. Ten treatments containing different concentrations of essential oil and ethanol extract (100.0; 50.0; 25.0; 12.5 and 6.3 mg.mL ) and the control group (50% ethyl alcohol and 1% Tween solutions) were used for antimicrobial testing. The major constituents of the essential oil were p-cimeno (32.72%), 1.8-cineol (24.05%) and 4-terpineol (20.23%), which were determined by gas chromatographymass spectrometry and gas chromatography -flame ionization detector (CG-MS/FID). Ellagic acid and three flavonoids (rutin, quercetin and campferol) were detected in the ethanol extract by means of high performance liquid chromatography-photodiode array detector (HPLC-PDA). All strains showed sensitivity to the treatments with essential oil and the ethanol extract. The best response was obtained with A. zerumbet essential oil at a 100 mg.mL ) e o grupo controle (álcool etílico a 50% e Tween a 1%). Os constituintes majoritários do óleo essencial foram p-cimeno (32,72%), 1,8-cineol (24,05%) e 4-terpineol (20,23%), sendo esses determinados por cromatografia a gás acoplada a espectrometria de massas e cromatografia a gás com detector de ionização de chama (CG-EM/DIC). No extrato etanólico foi detectado o ácido elágico e três flavonoides: rutina, quercetina e campferol, por meio de cromatografia a líquido de alta eficiência acoplada a detector de arranjo de diodo (CLAE-DAD). Todas as cepas apresentaram sensibilidade aos tratamentos com óleo essencial e extrato etanólico. A melhor resposta foi obtida com o óleo essencial de A. zerumbet que, na concentração de 100 mg.mL -1 proporcionou inibição total do crescimento bacteriano. Esses resultados sugerem o potencial antibacteriano do óleo essencial e do extrato etanólico de A. zerumbet no controle da mastite bovina. Composição química e eficácia do óleo essencial e do extrato etanólico de Alpinia zerumbet sobre Staphylococcus aureus PALAVRAS-CHAVE:

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Section: Resultsunclassified

Composição química e eficácia do óleo essencial e do extrato etanólico de Alpinia zerumbet sobre Staphylococcus aureus

Castro

Lima

Vasconcelos³

et al. 2016

Arq. Inst. Biol.

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“…Furthermore, 1,8-cineole showed significant levels of synergistic interaction when combined with antimicrobial compounds such as chlorhexidine gluconate (CHG) against Staphylococcus aureus, S. aureus, Escherichia coli, Klebsiella pneumoniae, Enterococcus faecalis, and Candida albicans [38]. On the other hand, it has been determined that essential oils with a high safrole content (75-85%) such as that extracted from Piper xylosteoides [39] and that from Piper hispidinervum [40,41] present weak activity against Gram-positive and Gram-negative bacteria. Azuero, et al [42] evaluated the antimicrobial effect of methanolic extracts of P. carpunya leaves and determined a high antibacterial effect against E. coli and a weak effect against P. aeruginosa; however, no effect against S. aureus was determined.…”

Section: Discussionmentioning

confidence: 99%

Study of Volatile Secondary Metabolites Present in Piper carpunya Leaves and in the Traditional Ecuadorian Beverage Guaviduca

Valarezo

Rivera

Coronel

et al. 2021

Plants

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Piper carpunya Ruiz & Pav. is an aromatic shrub native to Ecuador, the leaves of which are used to prepare the traditional beverage Guaviduca. Different health benefits are attributed to the guaviduca beverage, which is consumed as a traditional and folk medicine. In this study, fresh P. carpunya leaves were collected in the winter and summer and subjected to hydrodistillation for the extraction of the essential oil. The guaviduca beverage was prepared by infusion in water and the volatile compounds were isolated by liquid–liquid extraction. Chemical composition and enantioselective analyses were performed by gas chromatography. The antibacterial activity was assayed against Gram-positive and Gram-negative bacteria. The scavenging radical properties of the essential oil was evaluated by 2,2-diphenyl-1-picrylhydryl (DPPH) and 2,2′-azinobis-3-ethylbenzothiazoline-6-sulfonic acid (ABTS) assays. The acetylcholinesterase inhibitory activity was measured using the spectrophotometric method. The chemical analysis allowed us to identify more than 98% of the compounds in all samples. The main constituent of the essential oil was 1,8-cineole (25.20 ± 1.31%) in P. carpunya collected in winter and (17.45 ± 2.33%) in P. carpunya collected in summer, while in the beverage, there was 14 mg/L. Safrole was identified in the essential oil (PCW 21.91 ± 2.79%; PCS 13.18 ± 1.72%) as well as in the beverage (2.43 ± 0.12 mg/L). Enantioselective analysis was used to investigate the enantiomeric ratio and excess of four chiral components. The essential oil presented a strong activity against Klebsiella pneumoniae with a MIC of 500 μg/mL and a very strong anticholinesterase activity with an IC50 of 36.42 ± 1.15 µg/mL.

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“…The essential oil of A. zerumbet is active against Gram (+) and (-) bacteria, as well as fungi (Lobato et al, 1989;Victório et al, 2009f). The antimicrobial activity of the essential oil from the flowers of A. zerumbet was patented by Morita in 1992.…”

Section: Biological Activitiesmentioning

confidence: 99%

Therapeutic value of the genus Alpinia, Zingiberaceae

Victório¹

2011

Rev. bras. farmacogn.

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Plants containing bioactive substances have increasingly become the object of research studies, particularly those plants with therapeutic value. Many species of the genus Alpinia provide a variety of medicinal properties, such as, Alpinia zerumbet (Pers.) Burtt et Smith and A. purpurata (Vieill) K. Schum, which have a significant presence in Brazil. These species have been commercialized in the food and cosmetic industries. However, their greatest importance arises from the medicinal properties of their essential oils containing flavonoids, terpenoids and kavalactones which have been used in folk medicine to treat, for example, arterial hypertension and inflammatory processes. In addition, such species are also used in multidisciplinary studies, including phytochemistry, ethnobotany and biology, indicating the key pharmacological role of this genus in everyday life. Therefore, this work aims to present a bibliographic review of the genus Alpinia and its significance in therapeutic applications.

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Atividade antimicrobiana de óleos essenciais da Amazônia

Cited by 10 publications

References 1 publication

Composição química e eficácia do óleo essencial e do extrato etanólico de Alpinia zerumbet sobre Staphylococcus aureus

Composição química e eficácia do óleo essencial e do extrato etanólico de Alpinia zerumbet sobre Staphylococcus aureus

Study of Volatile Secondary Metabolites Present in Piper carpunya Leaves and in the Traditional Ecuadorian Beverage Guaviduca

Therapeutic value of the genus Alpinia, Zingiberaceae

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