Óleos essenciais da Amazônia contendo Timol

Morais, Anselmo A.; Mourão, Jamil C.; Gottlieb, Otto R.; SILVA, M. LEÃO DA; Marx, M. C.; MAIA, J. G. SOARES; MAGALHAES, M. TAVEIRA

doi:10.1590/1809-43921972021045

Cited by 21 publications

(10 citation statements)

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“…The oil yields for fresh (CsO-f) and dried (CsO-d) plants of C. scoparioides were 3.4% and 3.3%, respectively, and were shown to be higher than those previously reported, 2,3 while the oils chemical composition seems like similar to former analysis in which thymol methyl ether (CsO-f, 39.6%, CsO-d, 47.7%), thymol (CsO-f, 40.0%, CsO-d, 26.4%), α-phellandrene (CsO-f, 12.1%, CsO-d, 14.3%) and p-cymene (CsO-f, 1.5%, CsO-d, 1.7%) were the main constituents, totalizing over 90%. In the fresh plant oil the percentage values of thymol and thymol methyl ether are similar while for the dried plant oil the percentage value of methyl thymol ether is two times higher than the thymol.…”

Section: Resultscontrasting

confidence: 57%

“…Similarly, the higher oil yields for this C. scoparioides sample might be explained by the environmental aspects of the plant collection site in comparison to previous analyses. 2,3 The volatiles identified in the plant oils are listed in Table 1. The sample oils of C. scoparioides (CsO-f and CsO-d) were assayed at 11.6, 23.3, 46.6, 93.3 and 186.5 µg mL -1 to determine the DPPH scavenging activity.…”

Section: Resultsmentioning

confidence: 99%

“…1 Previously, the main volatiles identified in the essential oils of C. scoparioides were thymol, methyl thymol, α-phellandrene and p-cymene. 2,3 The plant extract and the compound curcubitacin E isolated Antioxidant Capacity and Biological Activity of Essential Oil and Methanol Extract J. Braz. Chem.…”

Section: Introductionmentioning

confidence: 99%

“…1 Previously, the main volatiles identified in the essential oils of C. scoparioides were thymol, methyl thymol, α-phellandrene and p-cymene. 2,3 The plant extract and the compound curcubitacin E isolated from were identified as cell-adhesion inhibitors. 4 Another plant extract of C. scoparioides occurring in Colombia showed leishmanicidal activity at same range of glucantime control.…”

Section: Introductionmentioning

confidence: 99%

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Antioxidant capacity and biological activity of essential oil and methanol extract of Conobea scoparioides (Cham. & Schltdl.) Benth.

Rebelo¹,

Silva²,

Andrade³

et al. 2009

J. Braz. Chem. Soc.

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Os óleos essenciais da planta sub-aquática Conobea scoparioides (fresca e previamente seca) apresentaram rendimentos de 3,4 e 3,3%, respectivamente. Os principais constituintes identificados foram o éter metílico do timol (39,6 e 47,7%), timol (40,0 e 26,4%), α-felandreno (12,1 e 14,3%) e p-cimeno (1,5 e 1,7%), totalizando mais de 90% nos referidos óleos. A concentração de seqüestro do radical DPPH (CE 50 ) dos óleos e extrato foi de 46,7 ± 3,6 µg mL -1 para a planta fresca (CsO-f), de 56,1 ± 2,4 µg mL -1 para a planta seca (CsO-d), e de 23,0 ± 2,2 µg mL -1 para o extrato metanólico (CsE-d). O valor do extrato é comparável ao BHT (19,8 ± 0,5 µg mL -1 ), usado como padrão antioxidante. O valor médio dos óleos é duas vezes menor, mas igualmente importante como agente antioxidante. O teor de Fenólicos Totais (TP, 124,6 ± 8,7 mg GAE per g) e o Trolox Equivalente (TEAC, 144,1 ± 4,9 mg TE per g) do extrato metanólico confirmaram a significativa atividade antioxidante de C. scoparioides. Da mesma forma, nos bioensaios com larva de camarão (Artemia salina) o valor médio da concentração letal dos óleos (CL 50 , 7,7 ± 0,3 µg mL -1 ) foi dez vezes maior que no extrato metanólico (CL 50 , 77,6 ± 7,1 µg mL -1 ) mostrando importante atividade biológica.The essential oils of the sub-aquatic plant Conobea scoparioides (fresh and dried previously) showed yields of 3.4 and 3.3%, respectively. The main identified constituents were thymol methyl ether (39.6 and 47.7%), thymol (40.0 and 26.4%), α-phellandrene (12.1 and 14.3%) and p-cymene (1.5 and 1.7%), totalizing more than 90% of the oils. The DPPH radical scavenging activity (EC 50 ) of the oils and extract was 46.7 ± 3.6 µg mL -1 in the fresh plant (CsO-f), 56.1 ± 2.4 µg mL -1 in the dried plant (CsO-d), and 23.0 ± 2.2 µg mL -1 in the methanol extract. The extract (CsE-d)value is comparable to BHT (19.8 ± 0.5 µg mL -1 ) used as antioxidant standard. The mean value of the oils is twice smaller but equally important as antioxidant agent. The mean amount of Total Phenolics (TP, 124.6 ± 8.7 mg GAE per g) and the Trolox Equivalent (TEAC, 144.1 ± 4.9 mg TE per g) of the methanol extract confirmed the significant antioxidant activity of C. scoparioides. Similarly, in the brine shrimp bioassay (Artemia salina) the mean value of the lethal concentration for the oils (LC 50 , 7.7 ± 0.3 µg mL -1 ) was ten times higher than the methanol extract (LC 50 , 77.6 ± 7.1 µg mL -1 ) showing important biological activity.Keywords: Conobea scoparioides, Scrophulariaceae, pataqueira, thymol and thymol methyl ether, antioxidant capacity, cytotoxicity IntroductionThe Scrophulariaceae is a cosmopolitan family comprising nearly 400 genera and 4,500 species, with their dispersion centre in the temperate regions of the north hemisphere. There are few species occurring in the Amazon. is a native erect herb called "pataqueira" or "vassourinhado-brejo", growing wild in seasonally inundated areas, with opposite leaves, sometimes alternate, deltoid, ovalate or lanceolate, with serrate or crenate margins. The who...

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Section: Resultscontrasting

confidence: 57%

Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

“…1 Previously, the main volatiles identified in the essential oils of C. scoparioides were thymol, methyl thymol, α-phellandrene and p-cymene. 2,3 The plant extract and the compound curcubitacin E isolated from were identified as cell-adhesion inhibitors. 4 Another plant extract of C. scoparioides occurring in Colombia showed leishmanicidal activity at same range of glucantime control.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Antioxidant capacity and biological activity of essential oil and methanol extract of Conobea scoparioides (Cham. & Schltdl.) Benth.

Rebelo¹,

Silva²,

Andrade³

et al. 2009

J. Braz. Chem. Soc.

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“…It was even possible to identify that from these monoterpenes, four were oxygenated (1,8-cineole, carvacrol-methyl ether, thymol and carvacrol) ( Table 1). Silva et al (2010) analyzing the essential oil of Origanum vulgare L. e Morais et al (2011) studying the oil of Conobea scoparioides Benth. and Lippia origanoides H.B.K.…”

Section: Resultsmentioning

confidence: 99%

Chemical Composition and Allelopathyc Activity of Essential Oil of Lippia sidoides Cham

Marco

Teixeira

Simplício

et al. 2012

Chilean J. Agric. Res.

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The allelopathy is a process for which products of the secondary metabolism, as terpenes phenolic, of a certain vegetal intervene significantly, generally of antagonistic form, in the development of other species of plants. The objective of this work was to chemically characterize the essential oil of Lippia sidoides Cham. growing in the Cariri cearense region, Brazil, and evaluate the allelopathyc effect of this oil on the germination of lettuce (Lactuca sativa L.), arugula (Eruca sativa Mill.), and cauliflower (Brassica oleracea L.), in pre-plantation application. The monoterpene thymol (84.90%) has been identified as the principal constituent in the essential oil. The experiment was done in randomized complete block, in 4 × 3 factorial; being used four essential oil combinations applied in three different species in pre-plantation applications. Emergence velocity index (EVI), germination percentage and mean time to germination (MTG), had been analyzed through daily counting carried out until the 14 th day after sowing. Through qualitative analysis performed by gas chromatography coupled with mass spectrometry (GC/MS) were identified seven chemical constituents representing 97.82% of essential oil of L. sidoides, being that the constituent present in greater concentration in oil was the thymol (84.90%). Could be verified the occurrence of the negative allelopathyc effect of lettuce crop, because its present low EVI and greater MTG, for the other vegetable species there were no allelopathic effect.

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Essential oils fromConobea scoparioides (Cham. & Schltdl.) Benth.

MAIA¹,

Zoghbi²,

Andrade³

et al. 2000

Flavour Fragr. J.

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Óleos essenciais da Amazônia contendo Timol

Abstract: Sinopse Timol é o principal componente dos óleos essenciais destilados das folhas de Conobea scoparioides Benth. (Scrophulariaceae), com rendimento 0,6% e das partes aéreas do arbusto Lippia origanoides H.B.K. (Verbenaceae). Ambos os óleos contem, também, para-cimeno.

Cited by 21 publications

References 0 publications

Antioxidant capacity and biological activity of essential oil and methanol extract of Conobea scoparioides (Cham. & Schltdl.) Benth.

Antioxidant capacity and biological activity of essential oil and methanol extract of Conobea scoparioides (Cham. & Schltdl.) Benth.

Chemical Composition and Allelopathyc Activity of Essential Oil of Lippia sidoides Cham

Essential oils fromConobea scoparioides (Cham. & Schltdl.) Benth.

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