Estudo Do Derivado Do Óleo De Ricinus Communis L. (Mamona) Como Agente Biocida E Redutor Da Viscosidade Produzida Por Leuconostoc Mesenteroides Em Indústrias Sucroalcooleiras

Messetti,; Santos, Alexandra; Angelis, Dejanira Franceschi de; Chierice, Gilberto Orivaldo; Neto, Salvador Claro

doi:10.1590/1808-1657v77p3012010

Cited by 10 publications

(6 citation statements)

References 5 publications

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“…It is noteworthy that no difference between treatments was found in the count of C. albicans and S. aureus , two important species found in the denture biofilm. Studies have reported that the detergent properties of R. communis cause damage to the cell wall, resulting in loss of the constituents of cytoplasm and subsequent cell death 12 , 30 . These action mechanisms however need to be further investigated.…”

Section: Discussionmentioning

confidence: 99%

“…The presence of a hydroxyl group, a single point of unsaturation and a carboxyl group – three highly reactive functional groups in the ricinoleic acid present in the castor oil composition – give R. communis important oil-chemical potential. It may be subjected to various chemical processes to obtain by-products used in the pharmaceutical and cosmetic industry, in the production of lubricants, polymers, biodiesel 11 , 12 , and more specifically in medical and dental products. Although a few studies have focused on the use of R. communis in complete dentures, the available results are promising 2 , 4 , 19 , 20 , 22 , 23 , particularly at a concentration of 10% 10 , 22 , 23 .…”

Section: Introductionmentioning

confidence: 99%

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Clinical trial for evaluation of Ricinus communis and sodium hypochlorite as denture cleanser

et al. 2017

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The development of opportunistic infections due to poor denture hygiene conditions justified the search for effective hygiene protocols for controlling denture biofilm. Objective This study evaluated Ricinus communis and sodium hypochlorite solutions in terms of biofilm removal ability, remission of candidiasis, antimicrobial activity, and participant satisfaction.Material and Methods It was conducted a controlled clinical trial, randomized, double-blind, and crossover. Sixty-four denture wearers with (n=24) and without candidiasis (n=40) were instructed to brush (3 times/day) and immerse their dentures (20 min/day) in different storage solutions (S1 / S2: 0.25% / 0.5% sodium hypochlorite; S3: 10% R. communis; S4: Saline).The trial period for each solution was seven days and a washout period of seven days was used before starting the use of another solution. The variables were analyzed at baseline and after each trial period. The biofilm of inner surfaces of maxillary dentures was disclosed, photographed, and total and dyed areas were measured (Image Tool software). The percentage of biofilm was calculated. Remission of candidiasis was assessed by visual scale and score were attributed. Antimicrobial activity was assessed by the DNA-Checkerboard hybridization method. Patient satisfaction was measured using a questionnaire.Results S1 (4.41±7.98%) and S2 (2.93±5.23%) were more effective then S3 (6.95±10.93%) in biofilm remotion(P<0.0001). All solutions were different from the control (11.07±11.99%). S3 was the most effective solution in remission of candidiasis (50%), followed by S1 (46%). Concerning antimicrobial action, S1/S2 were similar and resulted in the lowest microorganism mean count (P=0.04), followed by S3. No significant differences were found with patient’s satisfaction.Conclusions 10% R. communis and 0.25% sodium hypochlorite were effective in biofilm removal, causing remission of candidiasis and reducing the formation of microbial colonies in denture surfaces. All solutions were approved by patients.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Clinical trial for evaluation of Ricinus communis and sodium hypochlorite as denture cleanser

et al. 2017

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“…Castor oil, a natural derivative of the Ricinus communis plant, has a long history of therapeutic use. [54][55][56][57] It possesses recognised anti-inflammatory, 58 anti-nociceptive, 59 antioxidant, [60][61][62] anti-microbial, 63,64 insecticidal properties, 65 with a good safety and tolerance profile. 66,67 Recently, castor oil has found application within commercial ophthalmic eyedrop preparations, proving effective in counteracting tear film lipid insufficiency and tear film instability, and showing potential in managing dry eye disease secondary to meibomian gland dysfunction, without reported side effects.…”

Section: Treatmentmentioning

confidence: 99%

“…The detergent properties of R. communis can damage cell membranes, resulting in loss of the constituent cytoplasm and subsequent cell death. 63,64 Castor oil has shown activity against a broad range of Gram-positive and Gram-negative bacteria and fungi, particularly S. aureus and Escherichia coli and in some instances, castor oil has proved effective against antibiotic-resistant organisms. Trace amounts of essential oils (such as glycosides) in castor oil likely contribute to its observed antibacterial properties.…”

Section: Anti-microbialmentioning

confidence: 99%

Therapeutic potential of castor oil in managing blepharitis, meibomian gland dysfunction and dry eye

Sandford

Müntz

Craig

2021

Clinical and Experimental Optometry

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The multifactorial pathogenesis and interrelationship of blepharitis, meibomian gland dysfunction and dry eye disease poses challenges to any therapeutic approach. Current treatments are mostly palliative, with success limited by perceived inefficacy and poor patient compliance. Castor oil, a natural derivative of the Ricinus communis plant, is widely used as an emollient in cosmetics and personal care products, drug delivery systems and wound dressings. Castor oil is deemed safe and tolerable, with strong anti-microbial, anti-inflammatory, anti-nociceptive, analgesic, antioxidant, wound healing and vaso-constrictive properties. Its main constituent, ricinoleic acid, has a bipolar molecular structure that promotes the formation of esters, amides and polymers. These can supplement deficient physiological tear film lipids, enabling enhanced lipid spreading characteristics and reducing aqueous tear evaporation. Studies reveal that castor oil applied topically to the ocular surface has a prolonged residence time, facilitating increased tear film lipid layer thickness, stability, improved ocular surface staining and symptoms. This review summarises the properties, current uses of, and therapeutic potential of castor oil in managing ocular surface disease. The biochemical, medicinal actions of castor oil are explored from the perspective of ocular surface pathology, and include microbial and demodectic over-colonisation, inflammatory and oxidative processes, as well as clinical signs and symptoms of dryness and discomfort.

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“…Conversely, castor oil, which is rich in ricinoleic acid, can interact with the microbial membrane and inhibit microbial growth by dissolving chitin, which is a component of cell membranes. It is a bactericidal agent against a range of bacteria and can be applied as an antibiotic (Jena & Gupta, 2012; Leonardo, Silva, Filho, Bonifácio, & Ito, 2001; Messeti, Santos, Angelis, Chierice, & Neto, 2010).…”

Section: Introductionmentioning

confidence: 99%

Essential oils in diets for Nile tilapia juveniles: Productive performance and plasmatic biochemistry

et al. 2020

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The objective of this study was to evaluate the inclusion of increasing levels of a commercial mix of essential oils (EOs) from cashew (Anacardium occidentale) and castor bean (Ricinus communis) as an additive in diets for Nile tilapia. Thus, 240 juveniles with an initial weight of 35.06 ± 1.02 g were distributed in a completely randomized design (four treatments and six replicates) in 24 cylindrical‐tapered tanks; the fish were fed for 60 days, four times a day, diets containing increasing levels of EO (0.10, 0.15 and 0.20%) and a control diet (without the additive). After the experimental period, the animals were desensitized, and an aliquot of blood was collected for the biochemical analysis; they were subsequently euthanized for the evaluation of productive performance and fillet chemical composition. No significant differences (p > .05) were observed in the analyses of productive performance, fillet chemical composition, and triglycerides, VLDL, total proteins, urea and glucose. However, significant differences (p < .05) were observed in the analyses of total cholesterol, HDL and LDL. Inclusion above 0.15 of the additive showed an improvement in the levels of lipoprotein carriers, increasing HDL levels and decreasing LDL values, without interfering with the fish productive performance.

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Estudo Do Derivado Do Óleo De Ricinus Communis L. (Mamona) Como Agente Biocida E Redutor Da Viscosidade Produzida Por Leuconostoc Mesenteroides Em Indústrias Sucroalcooleiras

Cited by 10 publications

References 5 publications

Clinical trial for evaluation of Ricinus communis and sodium hypochlorite as denture cleanser

Clinical trial for evaluation of Ricinus communis and sodium hypochlorite as denture cleanser

Therapeutic potential of castor oil in managing blepharitis, meibomian gland dysfunction and dry eye

Essential oils in diets for Nile tilapia juveniles: Productive performance and plasmatic biochemistry

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