Comparison of tru-cut biopsy and fine-needle aspiration cytology in an experimental alcoholic liver disease model

Adalı, Yasemen; Eroğlu, Hüseyin Avni; Makav, Mustafa; Karayol, Sunay Sibel; Güvendi, Gülname Fındık; Gök, Mustafa

doi:10.1590/1806-9282.66.8.1030

Cited by 5 publications

(2 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Liver biopsy is an essential procedure for the diagnosis and management of liver malignancies. One of the most reliable procedures is the core-biopsy using Trucut needle, it is superior to open biopsy as it is rapid easy and less traumatic [9,10,11,12]. However, in diagnosis of liver malignancies, hematoxylin and eosinstained tissue section alone does not provide sufficient information for reaching the definitive diagnosis and identification of the origin of tumor.…”

Section: Introductionmentioning

confidence: 99%

Value of core needle biopsy in histopathological and immunohistochemical assessment of liver tumors

Kadhim¹,

Al-Janabi

2022

ijhs

View full text Add to dashboard Cite

Introduction: Liver is the most commonly involved organ by metastatic disease. Secondary tumors are more frequent lesion forming more than 75%, while primary cancers of liver formed less than 25%. Imaging according to LI-RAD can give a clue for the nature of the primary lesion of live particularly hepatocellular carcinoma. Liver biopsy is still the golden standard surveillance for histopathological diagnosis of liver tumor; however, it is a traumatic procedure, but its value in reaching the definite diagnosis is superior to imaging technique. Tru cut biopsy is less traumatic than open biopsy and considered nowadays as the preferable technical way in sampling liver tissue that can be applied for both histopathology and immunohistochemistry. Secondary liver lesions were encountered to be originated from lung, breast, Pancreatobiliary tract and GIT, female genital tract, prostate and others. Objectives of the Study: To assess the efficacy of Tru cut biopsy for both histopathological examination and immunohistochemical study identification the type and origin of liver tumors. Methodology: This is a cross sectional study conducted in the Al-Sadr Teaching Hospital in Al-Najaf City, Iraq from January 2019 till December 2021.

show abstract

Section: Introductionmentioning

confidence: 99%

Value of core needle biopsy in histopathological and immunohistochemical assessment of liver tumors

Kadhim¹,

Al-Janabi

2022

ijhs

View full text Add to dashboard Cite

show abstract

“…Moreover, owners of these patients often refuse these procedures to avoid their anesthetic risks, which then make the diagnosis inconclusive and specific treatment impossible. Ultrasound-guided fine-needle sample collection for cytology is used as a primary assessment of liver disease in human and veterinary patients because of its simplicity, speed, and low risk for complications [13][14][15][16] and remains the most commonly used staging technique for metastatic lymphoma [17]. Aspiration of the liver is recommended for the detection of lymphoma r egardless of its ultrasonographic appearance [18].…”

Section: Introductionmentioning

confidence: 99%

Comparison of fine-needle cytologic diagnosis between the left and right liver lobes of dogs and cats with diffuse liver disease

et al. 2021

View full text Add to dashboard Cite

Background and Aim: Ultrasound-guided fine-needle sample collection for cytology with manual restraint is frequently used for the primary assessment of diffuse liver disease in veterinary patients in Thailand. For better diagnosis, repeated collection of samples ensures the collection of adequate, representative samples, which increase diagnostic accuracy. However, in those that are unable to receive general anesthesia, it is difficult to collect the samples from several liver locations in manually restrained dogs and cats. The study aimed to compare the cytologic diagnosis of the ultrasound-guided fine-needle non-aspiration technique between the left and right liver lobes in dogs and cats with neoplastic and non-neoplastic diffuse liver disease. Materials and Methods: This prospective study included 25 client-owned dogs and cats with diffuse liver diseases. Two liver samples were randomly collected from the left and right liver lobes under ultrasound guidance for cytologic examination. All slides were subsequently examined blindly by experienced pathologists for cytologic analysis with cytologic agreement scores (CASs). Results: Among all 50 samples obtained from ultrasound-guided fine-needle sample collection of the left and right liver, 78% were diagnostic and 22% were non-diagnostic. In the diagnostic group, 73.3% of fine-needle samples had concordant results between the left and right liver, which exhibited 100% cytologic agreement in lymphoma and 63.6% in non-neoplastic groups. Samples collected from the left liver had slightly higher CAS and higher cytologic quality than had those from the right liver lobe (p=0.053). Conclusion: The location and number of sample collections did not have a significant difference in the cytologic diagnosis of diffuse liver disease, especially in patients with lymphoma. For manually restrained patients, one time ultrasound-guided non-aspiration cytology procedure from the left liver lobe not only decreased restraint duration and minimized tissue trauma but also allowed for an adequate cytologic diagnosis in diffuse liver disease compared to multiple collections.

show abstract

Comment on “Comparison of tru-cut biopsy and fine-needle aspiration cytology in an experimental alcoholic liver disease model”

Ekmekçi¹

2020

Rev. Assoc. Med. Bras.

View full text Add to dashboard Cite

Comparison of tru-cut biopsy and fine-needle aspiration cytology in an experimental alcoholic liver disease model

Cited by 5 publications

References 18 publications

Value of core needle biopsy in histopathological and immunohistochemical assessment of liver tumors

Value of core needle biopsy in histopathological and immunohistochemical assessment of liver tumors

Comparison of fine-needle cytologic diagnosis between the left and right liver lobes of dogs and cats with diffuse liver disease

Comment on “Comparison of tru-cut biopsy and fine-needle aspiration cytology in an experimental alcoholic liver disease model”

Contact Info

Product

Resources

About