Expression of Myostatin (Mstn) and Myogenin (Myog) Genes in Zi And Rhine Goose and Their Correlation with Carcass Traits

Zhao, Xinyi; Li, M. Y; Xu, Shuonan; Sun, Jijia; Liu, G J

doi:10.1590/1806-9061-2017-0710

Cited by 5 publications

(3 citation statements)

References 15 publications

(12 reference statements)

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“…In mammals, treatment of adult mice with an inhibitory antibody to myostatin resulted in muscle hypertrophy, suggesting that myostatin is an important mechanism for muscle remodeling in adult animals (Whittemore et al, 2003). In poultry, myostatin tightly regulates pectoralis muscle mass and inhibition of myostatin dramatically increased pectoralis mass in chicken, turkey, domestic pigeon, duck, and Japanese quail (McFarland et al, 2006;Xu et al, 2013;Shin et al, 2015;Liu et al, 2019;Zhao et al, 2019;Kim et al, 2020). Phenotypic flexibility in wild, free-living, birds could be more complicated since birds can modify flight muscle independent of workload (Swaddle and Biewener, 2000) and changes in flight muscle mass can occur without training (Dietz et al, 1999).…”

Section: Myostatin Signaling Pathwaymentioning

confidence: 99%

Skeletal muscle and metabolic flexibility in response to changing energy demands in wild birds

2022

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Phenotypically plastic responses of animals to adjust to environmental variation are pervasive. Reversible plasticity (i.e., phenotypic flexibility), where adult phenotypes can be reversibly altered according to prevailing environmental conditions, allow for better matching of phenotypes to the environment and can generate fitness benefits but may also be associated with costs that trade-off with capacity for flexibility. Here, we review the literature on avian metabolic and muscle plasticity in response to season, temperature, migration and experimental manipulation of flight costs, and employ an integrative approach to explore the phenotypic flexibility of metabolic rates and skeletal muscle in wild birds. Basal (minimum maintenance metabolic rate) and summit (maximum cold-induced metabolic rate) metabolic rates are flexible traits in birds, typically increasing with increasing energy demands. Because skeletal muscles are important for energy use at the organismal level, especially to maximum rates of energy use during exercise or shivering thermogenesis, we consider flexibility of skeletal muscle at the tissue and ultrastructural levels in response to variations in the thermal environment and in workloads due to flight exercise. We also examine two major muscle remodeling regulatory pathways: myostatin and insulin-like growth factor -1 (IGF-1). Changes in myostatin and IGF-1 pathways are sometimes, but not always, regulated in a manner consistent with metabolic rate and muscle mass flexibility in response to changing energy demands in wild birds, but few studies have examined such variation so additional study is needed to fully understand roles for these pathways in regulating metabolic flexibility in birds. Muscle ultrastrutural variation in terms of muscle fiber diameter and associated myonuclear domain (MND) in birds is plastic and highly responsive to thermal variation and increases in workload, however, only a few studies have examined ultrastructural flexibility in avian muscle. Additionally, the relationship between myostatin, IGF-1, and satellite cell (SC) proliferation as it relates to avian muscle flexibility has not been addressed in birds and represents a promising avenue for future study.

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Section: Myostatin Signaling Pathwaymentioning

confidence: 99%

Skeletal muscle and metabolic flexibility in response to changing energy demands in wild birds

2022

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“…Therefore, it is probable that the fish utilized liver and gonadal energy stores to supplement their dietary needs during this period of restricted feeding (Jobling 1995). In the same way, Liu et al (2019) reported a decrease in the growing weight of fish subjected to feeding a low-protein diet (25%) once daily for 20 days. Because lipid is the predominant energy storage form in fish, the crude lipid content of muscle and viscera is significantly lower.…”

Section: Discussionmentioning

confidence: 65%

“…Each gene has evolved to control a specific area of myogenesis regulation. Zhao et al (2019) stated that any other MRFs could not compensate MYOG function.…”

Section: Introductionmentioning

confidence: 99%

Exploring the impacts of different fasting and refeeding regimes on Nile tilapia (Oreochromis niloticus L.): growth performance, histopathological study, and expression levels of some muscle growth-related genes

Elbialy

Gamal

Al‐Hawary

et al. 2022

Fish Physiol Biochem

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The current study investigated how different fasting and refeeding regimes would impact Nile tilapia growth performance, histopathological examination, and gene expression of myostatin, myogenin, GH, IGF-1, and NPYa. Nile tilapia fish (n = 120) were randomly allocated into four groups, including the control group fed on a basal diet for 6 weeks (F6), group A starved for 1 week and then refed for 5 weeks (S1F5), group B starved for 2 weeks and then refed for 4 weeks (S2F4), while group C starved for 4 weeks and then refed for 2 weeks (S4F2). Fasting provoked a decrease in body weight coincided with more extended starvation periods. Also, it induced muscle and liver histological alterations; the severity was correlated with the length of fasting periods. Gene expression levels of GH, MSTN, MYOG, and NPYa were significantly increased, while IGF1 was markedly depressed in fasted fish compared to the control group. Interestingly, refeeding after well-planned short fasting period (S1F5) modulated the histopathological alterations. To some extent, these changes were restored after refeeding. Restored IGF-I and opposing fasting expression profiles of the genes mentioned above thus recovered weights almost like the control group and achieved satisfactory growth compensation. Conversely, refeeding following more extended fasting periods failed to restore body weight. In conclusion, refeeding after fasting can induce a compensatory response. Still, the restoration capacity is dependent on the length of fasting and refeeding periods through exhibiting differential morphological structure and expressions pattern for muscle and growth-related genes. Graphical abstract

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Esophageal striated muscle hypertrophy and muscle fiber type transformation in MSTN knockout pigs

Jin

Choe

et al. 2022

Transgenic Res

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Expression of Myostatin (Mstn) and Myogenin (Myog) Genes in Zi And Rhine Goose and Their Correlation with Carcass Traits

Cited by 5 publications

References 15 publications

Skeletal muscle and metabolic flexibility in response to changing energy demands in wild birds

Skeletal muscle and metabolic flexibility in response to changing energy demands in wild birds

Exploring the impacts of different fasting and refeeding regimes on Nile tilapia (Oreochromis niloticus L.): growth performance, histopathological study, and expression levels of some muscle growth-related genes

Esophageal striated muscle hypertrophy and muscle fiber type transformation in MSTN knockout pigs

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