2017
DOI: 10.1590/1806-9061-2016-0397
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Abstract: A complete linkage disequilibrium between the SNP (SNP B) in BCDO2 gene and the yellow skin phenotype in European domestic chicken has been reported. Here, we genotyped the reported SNPs (SNP A, SNP B, and SNP C) of the BCDO2 gene in 183 Chinese Indigenous chickens from 11 breeds/populations, including 57 yellow, 17 white, and 109 black skin chickens. The frequency of all three SNPs were significantly different between yellow and white skin chickens (p<0.01). In black skin chickens, a high frequency of the het… Show more

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Cited by 3 publications
(2 citation statements)
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“…The BCO2 gene encodes beta-carotene dioxygenase 2, which cleaves carotenoids (colorful substance) to apocarotenoids (colorless substance) via an asymmetrical cleavage reaction ( Kiefer et al, 2001 ), is detected in many tissues and can affect color trait ( Lindqvist et al, 2005 ). Kong et al (2017) reported that the frequency of the reported SNPs (SNP A, SNP B, SNP C) of BCO2 was significantly different between yellow- and white-skinned. Using CRISPR/Cas9 to knock out the EcBCO2 gene can lead to a color change in the hepatopancreas of prawns ( Sun et al, 2020 ).…”
Section: Discussionmentioning
confidence: 99%
“…The BCO2 gene encodes beta-carotene dioxygenase 2, which cleaves carotenoids (colorful substance) to apocarotenoids (colorless substance) via an asymmetrical cleavage reaction ( Kiefer et al, 2001 ), is detected in many tissues and can affect color trait ( Lindqvist et al, 2005 ). Kong et al (2017) reported that the frequency of the reported SNPs (SNP A, SNP B, SNP C) of BCO2 was significantly different between yellow- and white-skinned. Using CRISPR/Cas9 to knock out the EcBCO2 gene can lead to a color change in the hepatopancreas of prawns ( Sun et al, 2020 ).…”
Section: Discussionmentioning
confidence: 99%
“…Due to the important functions of BCMO, the function loss of BCMO from mutation would result in hypercarotenemia in human [9]. Moreover, yellow skin of domesticated chickens has a signi cantly association with the variation in BCDO [11]. More importantly, a candidate ketolase gene encoded by a cytochrome P450 enzyme was identi ed as a key gene responsible for the red plumage and bill coloration in birds, which can convert carotenoids from yellow to red [12,13].…”
Section: Introductionmentioning
confidence: 99%