Association between the consumption of antioxidant nutrients with lipid alterations and cardiometabolic risk in adolescents

Abstract

Article based on the master thesis of LM NASCIMENTO, entitled "Prevalência de fatores de risco cardiovascular e sua associação com nutrientes em adolescentes". Universidade Federal do Piauí; 2017. Como citar este artigo/How A B S T R A C T ObjectiveThis study aimed at validating the associations between the consumption of antioxidant nutrients as well as lipid alterations and cardiometabolic risks in adolescents. MethodsThis cross-sectional study included 327 adolescents aged 14-19 years. Sociodemographic and dietary information, anthropometric and blood pressure measurements, and biochemical data were obtained. Cardiometabolic risk was calculated by aggregating the risk factors, which were expressed as the sum of Z-scores. Poisson regression was performed to estimate the prevalence ratios. ResultsIn boys, low intake of zinc was associated with elevated total cholesterol and triglyceride levels, whereas it was associated with low high-density lipoprotein cholesterol levels and high low-density lipoprotein cholesterol and total cholesterol levels in girls, thus indicating a cardiometabolic risk. Furthermore, low intake of copper was associated with high triglyceride levels and cardiometabolic risk in girls. The high prevalence ratios of high low-density lipoprotein cholesterol and total cholesterol levels and cardiometabolic risk were higher in those with low intake of vitamin A. Among girls, associations were also observed between lower intake of vitamin A and high triglyceride levels. Low intake of vitamin C among boys was associated with elevated high low-density lipoprotein cholesterol and triglyceride levels. Among girls, the intake of this vitamin was associated with lower low high-density lipoprotein cholesterol levels. In girls, low intake of vitamin E was associated with low low high-density lipoprotein cholesterol levels and high total cholesterol levels. ConclusionThe associations between antioxidant micronutrients as well as lipid alterations and cardiometabolic risk emphasize the importance of encouraging the consumption of foods that are rich in these nutrients to modulate lipid alterations and cardiometabolic risk.

Associação entre a ingestão inadequada de micronutrientes antioxidantes e concentrações lipídicas de adolescentes no Brasil

“…Esses dados podem justificados pela função exercida por essa vitamina no metabolismo lipídico, a qual está associada a proteção da peroxidação lipídica e com isso reduz os danos causados pelo estresse oxidativo. Com isso, sugere-se que o aumento do consumo dessa vitamina pode prevenir o surgimento de dislipidemias em adolescentes (Nascimento, et al, 2018;Guerendian, et al, 2015). Os resultados encontrados podem ser sustentados por estudos que investigaram essa relação em indivíduos dislipidêmicos e obtiveram dados semelhantes (García, et al, 2013;Rodrigues, Fernandes, Souza, Hermsdorff & Duarte, 2015;Barzegar-amini & Hamideh Ghazizadeh, 2019;Carvalho, et al, 2020), o que pode representar risco para o desenvolvimento de doenças como a aterosclerose.…”

Metabolic syndrome in adolescents and its association with diet quality

“…Moreover, dark-green and orange vegetables are sources of β-carotene, an important antioxidant (pro-vitamin A) [50]. The low consumption of antioxidant micronutrients is associated with lipid alterations and cardiometabolic risk in adolescents [51], being another indication for the insertion of dark-green and orange vegetables in the diet of adolescents, aiming to prevent MS.…”

Factores asociados con el perfil lipídico de adolescentes

“…Food insecurity is associated with high consumption of foods with a higher energy density, and with a low intake of fruits and vegetables, predisposing the individual to the appearance of cardiometabolic diseases 35 . Nascimento et al (2018) 36 demonstrated that the low consumption of antioxidant nutrients, many of which are present in foods of plant origin, was associated with lipid alterations in adolescents. Maternal schooling is another factor that relates to the health conditions of adolescents 7 .…”