2016
DOI: 10.1590/1678-775720160137
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Abstract: Tooth bleaching is a technique of choice to obtain a harmonious smile, but bleaching agents may damage the dental pulp.Objective:This study evaluated the inflammatory responses of human dental pulp after the use of two bleaching techniques.Material and Methods:Pulp samples were collected from human third molars extracted for orthodontic reasons and divided into three groups: control - no tooth bleaching (CG) (n=7); at-home bleaching with 15% carbamide peroxide (AH) (n = 10), and in-office bleaching with 38% hy… Show more

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Cited by 53 publications
(40 citation statements)
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“…In recent study, intense inflammation, macrophages migration, pulp damage and increased number of blood vessels after dental bleaching with high concentrated bleaching gel were observed (Vaz et al . ). Thus, it can be hypothesized that damage in the pulps of bleached rat molars can predict damage that could occur in human dental pulps.…”
Section: Discussionmentioning
confidence: 97%
“…In recent study, intense inflammation, macrophages migration, pulp damage and increased number of blood vessels after dental bleaching with high concentrated bleaching gel were observed (Vaz et al . ). Thus, it can be hypothesized that damage in the pulps of bleached rat molars can predict damage that could occur in human dental pulps.…”
Section: Discussionmentioning
confidence: 97%
“…Despite unparalleled results, tooth whitening with concentrated peroxides results in high rates of side effects and serious biological risks. 1 , 2 These side effects have led to increasingly restrictive regulations concerning the use of whitening products containing high concentrations of peroxide and even questions regarding the use of the procedure at all. 3 , 4 Alternatively, aesthetic improvements can also be achieved with whitening toothpastes.…”
Section: Introductionmentioning
confidence: 99%
“…[1][2][3][4][5][6] While generally regarded as a safe agent for these applications, H 2 O 2 has a strong oxidant potential. Its effects in teeth and pulpal tissues have been well studied; [22][23][24][25][26][27] The results of our study showed, for the first time, that, in both the osteoblast and gingival fibroblast cell lines tested, exposure to a 0.05-µg/ml solution of H 2 O 2 (10-fold lower than the reportedly safe concentration of 0.68 µg/ml) elicited a cell-viability decrease of up to 50% (P<0.05), thus rejecting the first two null hypotheses. This effect was more pronounced with longer incubation times.…”
Section: Resultsmentioning
confidence: 99%